摘要
目的探讨声触诊组织定量（VTQ）技术鉴别甲状腺良恶性结节的临床价值及其影响因素。方法回顾性分析210例共240个甲状腺结节的二维、彩色多普勒及VTQ图像，记录检查切面及结节最大径、内部血流、钙化及距离皮肤的深度，并测量横向剪切波速度（SWV），采用R0c曲线方法计算VTQ鉴别甲状腺良、恶性结节的价值，采用多元线性回归方法分析结节最大径、钙化、内部血流、距离皮肤的深度及扫查切面、病理类型对SWV值的影响。结果VTQ技术鉴别甲状腺良恶性结节的灵敏性为74．8％，特异性为73．4％，曲线下面积为O．799。多元线性逐步回归分析显示，结节的最大径、病理类型及内部血流与SWV值相关（P＜0．05），其中病理类型对swV值的影响最大（标准化回归系数为一O．312）。而微钙化、结节的深度、扫查切面对swV值无明显影响（P＞0．05）。结论VTQ技术能定量提供甲状腺组织的硬度信息，在甲状腺良恶性结节鉴别诊断方面具有一定的价值。甲状腺结节的病理类型、内部血流及最大径是SWV值的影响因素，而结节距离皮肤的深度、扫查切面及微钙化与SWV值无关。
Objective To explore the value of virtual touch tissue quantification （VTQ） elastography and its influencing factors in identifying benign and malignant thyroid nodules. Methods A retrospective analysis was conducted in 210 cases of 240 thyroid nodules. Their images, including 2D ultrasound, color Doppler flow imaging （CDFI） and VTQ elastography,were reviewed,and the scanning view, the maximum diameter of the nodule, inside blood flow, calcifications and its depth beneath the skin were recorded. The value of shear wave velocity（SWV） in identifying benign and malignant thyroid nodules was calculated using receiver operating characteristic （ROC） curve. The influences of the maximum diameter of the nodules, calcifications, internal blood flow, the depth beneath skin and scanning views as well as type of pathology on the value of SWV were analyzed using multiple linear regressions （MLR）.Results The sensitivity and specificity of VTQ in differential diagnosis of benign and malignant thyroid nodules was 74.8% and 73.4%, respectively,and the area under ROC curve was 0.799. MLR indicated that the maximum diameter of the nodule, the type of pathology and internal blood flow were correlated with the SWV value （ P〈0.05）, of which, the type of pathology was the important factor （standardized coefficient was -0.312）. Microcalcifications, the depth of the nodules located and the scanning surface were not significantly related to SWV value （ P〉0.05）.Conclusions VTQ can quantitatively provide the information on the hardness of thyroid tissue, which is of a definite value in the differential diagnosis of the nodules.The pathology of the nodule,its internal blood flow and maximum diameter are the factors that affect the value of SWV,and not its depth,scanning views and microcalcifications.
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第7期594-597,共4页
Chinese Journal of Ultrasonography
关键词
超声检查
甲状腺结节
声触诊组织定量技术
Ultrasonography
Thyroid nodules
Virtual touch tissue quantification
