摘要
目的：探讨卵巢恶性生殖细胞肿瘤的临床、病理特点及相关预后因素。方法回顾性分析我院2006年1月~2011年12月收治的31例卵巢恶性生殖细胞肿瘤患者的临床病理资料及与预后的关系,并结合相关文献进行预后分析。结果31例患者中有9例为卵巢畸胎瘤恶变,7例为卵巢未成熟畸胎瘤,6例患者为卵巢无性细胞瘤,5例患者为卵黄囊瘤,3例患者为胚胎癌,1例患者为卵巢混合性卵黄囊瘤和胚胎癌。多因素生存分析显示手术病理分期及病理类型是影响患者总的生存率的独立预后因素（P=0.018及P=0.021）。各种不同病理类型的卵巢恶性生殖细胞肿瘤生存率比较,差异有统计学意义（P=0.049）。结论卵巢恶性生殖细胞肿瘤手术病理分期越晚,患者生存率越低。不同病理类型的卵巢恶性生殖细胞肿瘤的预后不同。
Objective To investigate the clinical features, pathological characteristics and prognostic factors of the ma-lignant ovarian germ cell tumor. Methods There was a retrospective analysis about 31 patients of malignant ovarian germ cell tumor from Jan 2006 to Dec 2011,while clinic and pathological factors were analyzed,and the related litera-ture was prognostic analyzed. Results Nine cases were ovarian teratoma with malignant change in 31 patients. 7 cases were ovarian immature teratoma, 6 cases were ovarian dysgerminoma, 5 cases were yolk sac tumor, 3 cases were em-bryonal carcinoma, 1 patient was ovarian mixed yolk sac tumor and embryonal carcinoma. Multivariate survival analysis showed that operation pathological staging and pathological types were independent prognostic factors affecting overall survival rate for patients （P=0.018 and P=0.021）. A variety of different pathological types of malignant ovarian germ cell tumor survival rate, the difference was statistically significant （P=0.049）. Conclusion Operation and pathology of malignant ovarian germ cell tumor staging more late, the survival rate of the patients is low. Prognosis of ovarian malig-nant germ cell tumors of different pathological types is different.
出处
《中国现代医生》
2014年第24期7-10,共4页
China Modern Doctor
关键词
卵巢恶性生殖细胞肿瘤
治疗
预后
Malignant ovarian germ cell tumor Treatment Prognosis
