摘要
目的:探讨胸部肿瘤IGRT治疗中不同图像配准方法对摆位误差的影响。方法:医科达Synergy IGRT直线加速器分别治疗胸部肿瘤患者20例,每次治疗前均行CBCT扫描,重建获得的CBCT图像与原计划CT图像进行配准,分析X、Y、Z轴方向的平移误差及旋转误差,比较骨性配准、灰度值配准及手动配准间的差异。结果:20例胸部肿瘤患者治疗前共行384次CBCT扫描。手动配准、骨性配准、灰度值配准在X轴的平移误差分别为(0.01±0.29)cm、(0.04±0.31)cm、(-0.02±0.28)cm,在Y轴的平移误差分别为(0.11±0.41)cm、(0.12±0.45)cm、(0.09±0.41)cm,在Z轴的平移误差分别为(-0.11±0.23)cm、(-0.05±0.22)cm、(-0.08±0.23)cm;X轴的旋转误差分别为(0.61±1.09)°、(0.34±1.44)°、(0.66±1.28)°,在Y轴的旋转误差分别为(0.06±0.83)°、(0.04±1.89)°、(0.16±1.6)°,在Z轴的旋转误差分别为(-0.17±1.45)°、(-0.19±1.53)°、(-0.13±1.45)°。结果显示手动配准、骨性配准和灰度值配准三种方式之间存在明显的差异。结论:胸部肿瘤患者行IGRT时,需要根据病变具体部位选择配准方式,建议自动配准后必要时结合手动微调,直到配准结果符合要求。
To investigate the optimal alignment methods for the treatment of thoracic tumor in IGRT. Methods：All 20 thoracic tumor patients were treated with the Elekta Synergy IGRT system. KV - CBCT images re-ceived before every treatment fraction. The difference in bone alignment,grey value alignment and manual alignment was compared. Results：Total of 384 sets of CBCT images were analyzed for 20 thoracic tumor patients. The mean ± standard deviation in the X,Y and Z axis directions were（0. 01 ± 0. 29）cm,（0. 04 ± 0. 31）cm,（ - 0. 02 ± 0. 28） cm;（0. 11 ± 0. 41）cm,（0. 12 ± 0. 45）cm,（0. 09 ± 0. 41）cm;（ - 0. 11 ± 0. 23）cm,（ - 0. 05 ± 0. 22）cm,（ - 0. 08 ± 0. 23）cm in thoracic tumor with bone alignment,grey value alignment and manual alignment respectively. The mean ± standard deviation in the X,Y and Z rotation directions were（0. 61 ± 1. 09）°,（0. 34 ± 1. 44）°,（0. 66 ± 1. 28）°;（0. 06 ± 0. 83）°,（0. 04 ± 1. 89）°,（0. 16 ± 1. 6）°;（ - 0. 17 ± 1. 45）°,（ - 0. 19 ± 1. 53）°,（ - 0. 13 ± 1. 45）° in thoracic tumor with bone alignment,grey value alignment and manual alignment respectively. There was significant difference among the three alignments. Conclusion：There exists some extent of setup error in 3DCRT or IMRT of tho-racic tumor patients. Alignment can be choiced based on the disease region. It is suggested that manul adjustment after automatic alignment is necessary.
出处
《现代肿瘤医学》
CAS
2014年第8期1910-1913,共4页
Journal of Modern Oncology
基金
广西研究生教育创新计划(编号:2010105981002D30)
广西卫生厅自筹经费科研课题(编号:Z2011207)
