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α-1,6岩藻糖基转移酶与甲胎蛋白异质体在原发性肝癌诊断中的应用 被引量:3

The value of α- 1,6- fucosyltransferase and alpha- fetoprotein variant in diagnosis of primary liver cancer
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摘要 目的:分析α-1,6岩藻糖基转移酶(FUT8)与甲胎蛋白异质体(AFP-L3)在原发性肝癌(PLC)诊断中的应用价值。方法:采用酶联免疫吸附试验(ELISA)方法分别检测我院92例PLC患者和42例非原发肝癌(NPLC)患者血清中FUT8和AFP-L3。结果:经统计学分析,PLC组与NPLC组血清FUT8和AFP-L3比较差异有统计学意义(P<0.05)。结论:α-1,6岩藻糖基转移酶(FUT8)与甲胎蛋白异质体(AFP-L3)在原发性肝癌(PLC)诊断中有一定的应用价值。 To study the value of α - 1,6 - fucosyltransferase and alpha - fetoprotein variant in diagno-sis of the primary liver cancer(PLC). Methods:By using enzyme linked immunosorbent assay(ELISA),detecting the FUT8 and AFP - L3 in sera of 92 cases of PLC patients and 42 cases of non - primary liver carcinoma(NPLC). Re-sults:Through statistical analysis,serum FUT8 and AFP - L3 had significant difference between PLC group and NPLC group(P ﹤ 0. 05). Conclusion:α - 1,6 - fucosyltransferase and alpha - fetoprotein variant have some value in the di-agnosis of primary liver cancer(PLC).
出处 《现代肿瘤医学》 CAS 2014年第8期1897-1898,共2页 Journal of Modern Oncology
关键词 原发性肝癌(PLC) α-1 6岩藻糖基转移酶(FUT8) 甲胎蛋白异质体(AFP-L3) primary liver cancer α - 1,6 - fucosyltransferase alpha - fetoprotein variant
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  • 1Bing-Hui Yang, Jing-Lin Xia, Li-Wen Huang, Zhao-You Tang, Ming-Shan Chen, Jin-Qing Li, An-Min Liang, Qin-Guo Mo, Hui-Shan Lu, Chao-Liu Dai, Lu-Nan Yan, Zhi-Jian Yu, Rong-Sheng Rao, Le-Qun Li, Zhi-Xiong Su, Zhuang-Wei Fang Shanghai, China Liver Cancer Institute & Zhongshan Hospital, Fudan University, Shanghai 200032, China,Tumor Hospital, Zhongshan University, Guangzhou 510000, China Tumor Hospital, Guangxi Medical Universi- ty, Nanning 530000, China,Xiehe Hospital, Fujian Medical University, Fuzhou 350000, China,Second Hos- pital, Chinese Medical University, Shenyang 110000, China ,Huaxi Hospital, Sichuan University, Chengdu 610041, China ,Hospital Affiliated to Nantong Medical University, Nantong 226000 , China,Second Hospital, Jiangxi Medical University, Nanchang 330000 , China ,First Hospital Affiliated to Guangxi Medical University, Nanning 530000 , China ,People’s Hospital of Hainan Province, Haikou 570000, China.Changed clinical aspects of primary liver cancer in China during the past 30 years[J].Hepatobiliary & Pancreatic Diseases International,2004,3(2):194-198. 被引量:20

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