摘要
目的探讨糖尿病性脑血管病患者与情绪障碍的高危险因素及其对预后的影响。方法将133例糖尿病性脑血管伴发情绪障碍的患者作为观察组;选择同时间就诊的129例无情绪障碍的糖尿病性脑血管病患者作为对照组;并比较两组的临床效果。结果两组患者FBG、PBG、HbA1C随治疗进行明显下降,观察组FBG治疗4周、24周后与对照组比较(t1=2.69,t2=2.90,P<0.05);观察组的神经缺损程度和生活质量治疗前均重于对照组(t3=27.10,t4=-28.61,P<0.05);观察组随着治疗的进行神经缺损程度与情感障碍得到明显改善(t4w=7.76,t24w=8.13,均P<0.05);观察组随着治疗的进行生活质量逐渐的明显改善(t4w=-12.26,t24w=-13.12,均P<0.05);观察组的SAS和SDS评分随治疗的进行逐渐降低,在4周、24周后与治疗前比较(SAS:t4w=7.37,t24w=7.10,SDS:t4w=5.85,t24w=5.58,P均<0.05))。结论情绪障碍的改善,有助于患者的血糖控制,可明显降低脑血管疾病的发生率和死亡率,可有效促进神经功能的康复及患者生活质量的提高。
Objective To explore high-risk factors and their effects on prognosis for patients with diabetic cerebrovascular disease and emotional disorders. Methods 133 patients with diabetic cerebrovascular disease complicated with emotional disorders were selected as an observation group;129 patients with diabetic cerebrovascular disease yet without emotional disorders who were diagnosed at the same period were selected as a control group. Clinical efficacy was compared between the two groups. Results FBG, PBG and HbA1C in the two groups significantly reduced with the treatment going on. FBG in the observation group at week 4 and week 24 of the treatment were compared with those in the control group（t1=2.69, t2=2.90, P〈0.05）; nerval functional defects and life quality in the observation group before the treatment were both more severe than those in the control group（t3=27.10, t4=-28.61, P 〈 0.05）; nerval functional defects and emotional disorders in the observation group greatly alleviated with the treatment going on（t4w=7.76, t24w=8.13, P〈0.05 for both）;SAS and SDS scores in the observation group gradually lowered with the treatment going on, and the scores at week 4 and week 24 were compared with those before the treatment（SAS： t4w=7.37, t24w=7.10, SDS： t4w=5.85, t24w=5.58, P〈0.05 for all）. Conclusion Alleviation of emotional disorders helps control patients’blood sugar, significantly reduce incidence and mortality of cerebrovascular diseases and effectively promote the recovery of nerval functions and patients’life quality.
出处
《中国医药科学》
2014年第14期10-12,共3页
China Medicine And Pharmacy
基金
广东省佛山市科技局立项课题(2014346)
关键词
糖尿病性脑血管病
焦虑
抑郁
相互关系
Diabetic cerebrovascular disease
Anxiety
Depression
Interrelations
