摘要
目的利用聚类分析和社会网络分析的方法分析儿童及青少年分泌性中耳炎当前主要的治疗措施。方法采用gopubmed数据库的统计方法分析获取研究的基本特征,并根据检索结果绘制发表时间曲线和发表地域的世界图。采用聚类分析和社会网络分析法分析中耳炎当前主要的治疗措施。采用gcluto进行聚类分析,采用Ucinet 6.0软件中的NetDraw按照中心度排列各个主题词之间的关系,并绘制社会网络图。结果共纳入328个研究。聚类分析将当前中耳炎的治疗措施分为3类:研究主题1(β-内酰胺类和大环内酯类抗生素)、研究主题2(手术治疗和术后预防性应用抗生素)和研究主题3(其他抗生素治疗)。社会网络分析显示,抗生素治疗和手术治疗居于治疗网络的核心位置。结论当前中耳炎的主要治疗措施为抗生素治疗和手术治疗。急、慢性和不同年龄阶段儿童及青少年分泌性中耳炎在治疗上即有共性,也存在差异。临床实践中,应根据不同的年龄和病程选择具体的治疗措施。
Objective To analyze the current treatment for children and teenagers with otitis media with effusion by using cluster analysis and social network analysis methods.Methods Gopubmed database was used to analyze the basic features of randomized controlled trials about otitis media and to draw published time curve and the study map.Gcluto software was used to conduct cluster analysis,and social network analysis was conducted by using NetDraw from Ucinet 6.0 software.Results A total of 328 studies were included.There were three clusters：research theme 1 （β3-lactam and macrolide antibiotics）,research theme 2 （surgical treatment and antibiotic prophylaxis）,and research topic 3 （other therapeutic drugs）.Social network analysis showed that the antibiotic therapy and surgery were in the core of the network of treatments.Conclusions Cluster analysis and social network analysis shows that the current main treatments of otitis media with effusion are antibiotics and surgery.Although there was common treatments in acute and chronic,infant,preschool child,and adolescent otitis media with effusion,there are also differences.Therefore,treatments for children with otitis media with effusion should be selected based on disease duration and age in the clinical practice.
出处
《中国眼耳鼻喉科杂志》
2014年第4期223-229,共7页
Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词
抗生素治疗
手术
中耳炎
知识可视化
Antibiotic treatment
Surgery
Otitis media
Knowledge visualization
