摘要
目的应用氢质子磁共振波谱（1H-MRS）技术,探讨正常成年人腰椎（L1~L4）椎体的脂水比（LWR）和脂肪含量（FF%）与性别、年龄及体质量指数（BMI）之间的关系。方法选择100例MRI检查正常的成年人,其中男性52例（52%）,女性48例（48%）;年龄18~79岁,平均年龄46.77岁;平均BMI为22.85。按性别、年龄及BMI进行分组：男性组52例,女性组48例：青年组（≤44岁）44例,中年组（45~59岁）33例,老年组（≥60岁）22例;正常组（18.5〈BMI〈24.0）69例,超质量肥胖组（BMI≥24）31例。所有纳入对象行MRI常规扫描及L1~L4椎体的1H-MRS扫描,测量并记录椎体的LWR及FF%,采用SPSS13.0对所有数据按组别进行统计学分析。结果 L1~L4椎体的平均LWR及FF%分别为1.20±0.75、1.41±0.93、1.57±1.05、1.58±1.09和0.50±0.15、0.53±0.15、0.56±0.15、0.56±0.15,LWR及FF%在性别及年龄组间的差异具有统计学意义（P〈0.05）,而BMI组间差异不具有统计学意义（P〉0.05）;相关性分析结果显示,L1~L4椎体的LWR和FF%与年龄呈正相关（P〈0.05,相关系数为0.47~0.54）,但与BMI没有相关性（P〉0.05）。结论 L1~L4各椎体的LWR和FF%均存在性别差异（男性高于女性）,并随着年龄的增加而增大。
Objective To explore the relationship between the lipid-water ratio（LWR） and fat fraction%（FF%） of normal adult vertebral body L1- L4and gender, age, body mass index（BMI） by the technique of proton magnetic resonance spectroscopy（1H-MRS）.Methods A total of 100 cases with normal lumber vertebral body met the inclusion and exclusion criteria were enrolled, which included 52 males（52 %） and 48 females（48 %）, aged 18- 79 years old with mean age of 46.77 and mean BMI of 22.85. Based on the gender, they were divided into male group（n = 52） and female（n = 48） group; Based on the age, they were divided into youth group（n =44, aged ≤ 44-year-old）, middle-aged group（n = 33, aged 45- 59-year-old） and older age group（n = 22, aged ≥ 60-year-old）;Based on the BMI, they were divided into normal group（n = 69, 18.5 ＆lt; BMI ＆lt; 24） and super obese group（n = 31, BMI ≥ 24）. All of them were performed routine magnetic resonance imaging（MRI） scan and proton magnetic resonance spectroscopy. The values of LWR and FF% of vertebral body L1- L4in various group were measured and recorded respectively. The statistical analysis was carried out by SPSS 13.0. Results The LWR and FF% of normal vertebral body L1- L4were 1.20 ± 0.75, 1.41 ± 0.93, 1.57 ±1.05, 1.58 ± 1.09 and 0.50 ± 0.15, 0.53 ± 0.15, 0.56 ± 0.15, 0.56 ± 0.15, respectively. There was statistical significance difference in gender group and age group（P ＆lt; 0.05）, but there was no statistical significance difference in BMI group（P ＆lt; 0.05）. The correlation analysis showed that LWR and FF% of L1- L4existed positive correlation with age（P ＆lt; 0.05, correlation coefficients =0.47- 0.54）, but non-correlation with BMI（P ＆gt; 0.05）. Conclusion It is demonstrated that the LWR and FF% of normal vertebral L1- L4exists gender differences（males higher than females）, and the difference increases with age.
出处
《生物医学工程与临床》
CAS
2014年第4期338-343,共6页
Biomedical Engineering and Clinical Medicine
基金
四川省卫生厅科研课题(100153)
关键词
氢质子磁共振波谱
腰椎椎体
水峰
脂肪峰
脂肪含量
proton magnetic resonance spectroscopy
lumber vertebral body
water peak
lipid peak
fat fraction/content
