摘要
目的评价机械通气患者密闭式与开放式吸痰的效果。方法 2012年10-12月,采用计算机检索Cochrane图书馆、JBI图书馆、Pubmed(1966-2012)、EMbase(1989-2012)、中国生物医学文献数据库(1978-2012)、维普数据库(1989-2012)中机械通气患者进行密闭式和开放式吸痰效果比较的随机对照试验(randomized control trial,RCT)文献,同时筛查纳入文献的参考文献。由3名研究者分别对文献进行质量评价和资料提取,对纳入的RCT进行Meta分析。结果最终纳入10篇RCT文献。Meta分析结果显示,密闭式与开放式吸痰相比在降低呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)的发生率、延长置管至VAP发生时间上的差异均有统计学意义(均P<0.05),而在病死率、机械通气、时间长短上的差异无统计学意义(P>0.05)。结论密闭式吸痰有助于降低呼吸机相关性肺炎的发生率,延长置管至VAP发生的时间。
Objective To evaluate the effects of closed tracheal suction systems（CTSS）versus open tracheal suction systems（OTSS）in mechanically-ventilated patients.Methods The Cochrane Library,Joanna Briggs Institute Library,Pubmed（1966to 2012）,EMbase（1989to 2012）,Sinomed（1978to 2012）,and Vip Information（1989to 2012）were searched in order to collect RCTs.The quality of RCTs was critically appraised and data were extracted by 3reviewers independently.Meta-analysis was conducted for the eligible RCTs.Results Ten RCTs were included.The outcomes of meta-analysis showed that there was significant difference on the incidence of VAP and the duration from intubation to the development of VAP（all P〈0.05）.The outcomes demonstrated no significant difference on the rate of mortality,duration of ventilation between the two groups（P〉0.05）.Conclusion Compared with OTSS,CTSS can decrease the incidence of VAP and delay the development of VAP from intubation.
出处
《解放军护理杂志》
CSCD
2014年第14期1-6,共6页
Nursing Journal of Chinese People's Liberation Army
关键词
机械通气
密闭式吸痰
开放式吸痰
系统评价
mechanical ventilation
closed tracheal suctioning
open tracheal suctioning
systematic review
