摘要
目的探讨亚低温辅助治疗颅内感染合并高热临床效果,以期提高临床治疗水平。方法随机选取2009年1月-2012年1月90例颅内感染合并高热患者为研究对象,将其随机分成两组,对照组45例采用常规治疗,观察组45例在对照组基础上加用亚低温辅助治疗,比较两组治疗后的临床效果。结果对照组显效率46.7%、总有效率为77.8%;观察组的显效率71.1%、总有效率为91.1%;两组治疗后在体温、呼吸、心率、血压、SpO2和炎性指标C-反应蛋白、血沉、降钙素原比较,差异均有统计学意义(P<0.05)。结论亚低温辅助治疗颅内感染合并高热不仅能短时间内降低体温,且能抑制感染。
OBJECTIVE To investigate the clinical effects of adjuvant treatment with mild hypothermia for inturacranial infections accompanied by hyperpyrexia, in order to improve the level of clinical treatment. METHODS Totally 90 patients with intracranial infections accompanied by hyperpyrexia in Jan. 2009- Jan. 2012 were randomly selected in this study and were divided into two groups. The control group of 45 patients received conventional treatment, while the observation group of 45 patients received adjuvant treatment with mild hypothermia based on the treatment in the control group, clinical results were compared after treatment. RESULTS The efficiency rate and the total effective rate was 46.7%, 77.8% in the control group and 71.1%, 91.1% in the observation group. The difference was significant in body temperature, respiration, heart rate, blood pressure and SpO2 and inflammatory markers C-reactive protein, blood sedimentation, calcitonin between two groups after treatment （P〈 0.05）. CONCLUSION Adjuvant treatment with mild hypothermia for intracranial infection accompanied by hyper-pyrexia can not only lower body temperature within a short time, but also can inhibit infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第15期3739-3741,共3页
Chinese Journal of Nosocomiology
基金
海南省卫生厅重点计划基金资助项目(HW-2010B-038)
关键词
亚低温
颅内感染
高热
临床效果
Mild hypothermia
Intracranial infection
Hyperpyrexia
Clinical effects
