摘要
目的探讨凝血指标异常在老年缺血性脑血管病中的临床意义。方法测定81例老年缺血性脑血管病患者和54例健康老年人凝血酶原时间(PT)、凝血酶时间(TT)、活化的部分凝血活酶时间(APTT)、血浆纤维蛋白原(FIB)和D-二聚体(D-Dimer,DD)等参数的变化,结合临床资料分析其临床意义。结果与对照组相比,老年缺血性脑血管病患者急性期PT、TT、APTT明显缩短,DD和FIB明显增高(P<0.05);稳定期PT、TT、APTT均比急性期延长,DD和FIB与急性期患者相比有所下降,但仍高于对照组(P<0.05)。结论凝血功能异常与老年缺血性脑血管病的发生密切相关,动态监测老人各项凝血指标的变化可为老年缺血性脑血管病的防治提供一定的依据。
Objective To explore the clinical significance of blood coagulation disorder in the senile ischemic cerebrovascu-lar disease .Methods The levels of prothrombin time （PT）,thrombin time （TT）,activated partial thromboplatin time （APTT） ,fibrinogen （FIB） and D-dimer （DD） in 81 cases of elderly patients with ischemic cerebrovascular disease and 54 healthy old people were detected and the clinical significance of which was analyzed in combination with the clinical data .Results In acute stage ,PT ,TT and APTT in elderly patients with ischemic cerebrovascular disease were shorter and the levels of DD and FIB were significantly higher than those in control group （P〈0 .05） .PT ,TT and APTT in stationary phase were longer than those in acute stage （P〈0 .05） .The levels of DD and FIB in stationary phases were much lower than those in acute stage , but were still higher than those in control group （P〈0 .05） .Conclusion The blood coagulation disorder is closely related with the development of ischemic cerebrovascular disease in old man .Dynamically monitoring the coagulation index may provide a certain basis for prevention and treatment of senile ischemic cerebrovascular disease .
出处
《中国实用神经疾病杂志》
2014年第15期7-8,共2页
Chinese Journal of Practical Nervous Diseases
