摘要
目的探讨贵州苗药组方的荞笋消萎饮对慢性萎缩性胃炎(CAG)治疗的临床疗效。方法将符合诊断标准的72例患者,随机分为荞笋消萎饮治疗组与胃复春对照组,分别治疗3个月。观察两组患者治疗前后临床症状积分、胃镜及病理情况以及P53、GST-π积分的变化情况。结果治疗组临床症状较对照组有明显改善,胃镜及病理改变也优于对照组,其中胃黏膜肠上皮化生与萎缩的变化具有显著性差异;两组治疗前后P53、GST-π的蛋白表达积分也有明显的变化。结论荞笋消萎饮对CAG的临床症状、胃镜及病理变化、P53、GST-π的蛋白表达积分有明显的改善作用。
Objective To observe the clinical effect of treating CAG with taking Qiaosunxiaowei Yin, a prescription from Miao medicine in Guizhou province. Methods Through dividing randomly 72 cases which meet the diagnostic criteria into 2 groups, one is treatment group which takes Qiaosunxiaowei Yin（ n = 36）, the other one is control group takes Weifuchun tablet（ n = 36）. After treating for 3 months, comparing the changes of integral like clinical symptom, presentation of pathology and gastroscope, expres- sion of P 53 and GST - Лwith treatment before. Results We find out that there is obvious improvement in treatment group compa- ring to control group, and the expression of P 53 and GST - Лof two groups also improved evidently. Conclusion It was sugges- ted that Qiaosunxiaowei Yin can obviously improve clinical symptom, presentation of pathology and gastroscope and expression of P 53 and GST- Л.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2014年第7期1667-1669,共3页
Lishizhen Medicine and Materia Medica Research
基金
贵州省中医药管理局中医药
民族医药科学技术研究课题(No.QZYY2011-44)
