摘要
目的:探讨基于大鼠中脑P物质(Substance P,SP)及其受体变化研究针刺治疗偏头痛的机制的可行性。方法:根据SP及其受体在疼痛过程中的现状及针刺治疗脑部疾病的优势,通过测定大鼠中脑的SP及受体的变化揭示针刺治疗偏头痛的应用构想。结果:基于大鼠中脑SP及其受体变化可以揭示针刺治疗偏头痛的作用机制。结论:通过观察针刺大鼠脑内SP及其受体表达的变化阐明针刺治疗偏头痛的作用机理是可行的研究路径,能为临床提供理论依据。
To explore the application of substance P （SP）in rats mesencephalon to explain the mechanism of acupuncture for migraine.Methods：According to the present studies on change of SP and receptors during the pain and the dominant position of acu-puncture for brain diseases,the study prospects and application process based on the change of SP and receptors were introduced.Re-sults：The change of SP and receptors could explain the mechanism of acupuncture for migraine.Conclusion：The application of SP and receptors are supposed to be available ways to explain the mechanism of acupuncture for migraine,which can provide a theory base to clinical research.
出处
《世界中医药》
CAS
2014年第7期961-964,共4页
World Chinese Medicine
基金
首都医科大学中医药护理专项(编号:12ZYH04)
关键词
针刺
偏头痛
SP
Acupuncture
Migraine
Substance P
