摘要
目的探讨电生理参数异常分布用于诊断格林巴利综合征的价值。方法选取40例格林巴利综合征患者作为研究对象，进行电生理检查。记录肢体两侧、上下肢及远近端运动神经末端潜伏期（DML）、运动传导速度（MCV）、肌肉复合动作电位（CMAP）和感觉传导速度（SCV）。结果F波潜伏期轻度异常、中度异常及重度异常分别为18．3％、6．2％和5．3％，合计29．8％；F波出现率轻度异常、中度异常及重度异常分别为9．3％、9．8％和15．6％，合计66．9％。感觉传导速度异常率为57．5％，运动传导速度异常率为75．7％，两组差异具有统计学意义（x^2=5．34，P〈0．05）。双侧胫神经检测显示轻、中、重型患者H-反射异常率分别为78．0％、80．9％和100．0％，三者问差异无统计学意义（Uc=1．47，P〉0．05）。近端和远端运动神经重度受损率分别为48．3％和74．5％，两者差异具有统计学意义（x^2=9．86，P〈0．05）。上肢近端神经重度受损率为51．4％，显著低于上肢远端的71．6％，下肢近端神经重度受损率为44．2％，显著低于下肢远端的81．6％，差异均有统计学意义（x^2=8．86、12．43，均P〈0．05）。结论电生理参数检测对格林巴利综合征的诊断具有较高价值，可以准确反应患者神经功能受损情况。
Objective To investigate diagnosis value of abnormal distribution of electrophysiological parameters in Guillain-Barre syndrome. Methods 40 cases of Guillain-Barre syndrome were chosen as an object of study, all patients electrophysiological examination. Record limbs on both sides, upper and lower extremities and proximal and distal motor nerve distal latency （ DML）, motor conduction velocity （ MCV ）, compound muscle action potential （CMAP） and sensory conduction velocity（SCV） were recorded. Results F wave latency mildly abnormal, moderately abnormal and severe abnormalities were 18.3 % ,6.2 % and 5.3 %, totaling 29.8 %, F-wave occurrence rate mildly abnormal,moderately abnormal and severe abnormalities were 9.3 % 9.8% and 15.6% ,totaling 66.9%. Abnormal sensory conduction velocity was 57.5% ,motor conduction velocity anomaly was 75.7%, there was a statistically significant difference between the two groups （x^2 = 5.34, P 〈 0. 05 ）. bilateral tibial nerve tests showed mild, moderate and severe in patients with H-reflex abnormality rates were 78.0% ,80.9% and 100.0% ,among the three comparison （ Uc = 1.47 ,P 〉 0.05 ）. 3 proximal and distal motor nerve severe damage rates were 48.3 percent and 74.5 percent, the difference was statistically Significant （ x^2= 9.86, P 〈 0. 05 ）. Severe upper limb proximal nerve damage was 51.4%, significantly lower than 71.6% of the distal upper extremity, lower extremity proximal nerve severe damage to 44.2 % , significantly lower than the 81.6% of distal lower extremity between them were statistical difference （x^2 = 8.86,12.43, all P 〈 0.05 ）. Conclusion Electrophysiological parameters detection Guillain-Barre syndrome has a high value, which can be accurate response in patients with neurological damage.
出处
《中国基层医药》
CAS
2014年第14期2123-2125,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
格林巴利综合征
神经传导
生理
神经
Guillain-Barre syndrome
Nerve conduction
Physiology
Nerve
