摘要
目的:对比埃索美拉唑和奥美拉唑预防机械通气患者应激性溃疡的效果。方法:按照随机数字表随机将214例患者分为埃索美拉唑组(108例)、奥美拉唑组(106例)。观察治疗后一周内2组应激性溃疡的发生率。结果:埃索美拉唑组和奥美拉唑组的SU发生率分别为4.63%、12.26%,2组差异有统计学意义(P<0.05)。结论:埃索美拉唑较奥美拉唑能更有效预防机械通气患者应激性溃疡的发生。
Objective：To compare the effect of esomeprazole and omeprazole in preventing stress ulcer in mechanical ventilation patients. Method：According to the random number table, 214 cases of patients were randomly divided into the esomeprazole group （n= 108） and omeprazole group （n= 106）. The incidence of stress ulcer was observed within one week after treatment. Result：The incidence of stress ulcer in Esomeprazole group and ome- prazole group was 4.63 %, 12.26 % respectively, and its difference was statistically significant （P〈0. 05）. Conclusion： Esomeprazole could prevent stress ulcer in mechanical ventilation patients more effectively than omeprazole.
出处
《临床急诊杂志》
CAS
2014年第7期396-398,共3页
Journal of Clinical Emergency
基金
南京军区重点课题(No:12Z32)
全军医学科技青年培育项目(No:13QNP038)
关键词
应激性溃疡
埃索美拉唑
机械通气
预防
stress ulcers
esomeprazole
mechanical ventilation
prophylaxis
