摘要
目的:观察培哚普利联合苯磺酸氨氯地平治疗老年高血压的临床疗效。方法:选取120例老年高血压患者随机分为治疗组与对照组,其中治疗组患者60例,口服培哚普利加苯磺酸氨氯地平;对照组患者60例,口服培哚普利,观察并随访3个月,分别在治疗1个月、3个月末测量患者血压、降压达标率和不良反应,评价临床治疗效果。结果:经统计学分析,两组患者的血压水平与治疗前相比较均显著下降,治疗组患者的降压达标率在1个月、3个月末均高于对照组,P<0.05,两组患者的不良反应发生率相比较,无统计学差异,P>0.05。结论:培哚普利与苯磺酸氨氯地平联合治疗老年高血压疗效肯定,不良反应少,值得临床推广。
Objective:To observe clinical efficacy of perindopril and amlodipine besylate in treatment of elderly hypertension. Methods:120 elderly patients with hypertension were randomly divided into treatment group ( treated with perindopril and amlodipine besylate) and control group (treated with perindopril), with 60 cases in each group. They were observed and followed-up for 3 months. The blood pressure was measured at the end of 1 month and 3 months of the treatment for the pressure-lowering standard-re-searching rate and adverse reactions. Further, the clinical efficacy was evaluated. Results:Through the statistical analysis, the levels of blood pressure of all the patients after the treatment significantly decreased compared with those before the treatment. The pressure-lowering standard-researching rates of treatment group at the end of 1 month and 3 months of the treatment were higher than those of control group (P〈0. 05);however, there was no statistical difference in the incidence rate of adverse reactions between the two groups (P〉0. 05). Conclusions:Perindopril and amlodipine besylate in the treatment of elderly hypertension is more effect, has less adverse reactions, and is worthy of clinical promotion.
出处
《中国民康医学》
2014年第13期39-40,共2页
Medical Journal of Chinese People’s Health