摘要
目的分析我国肿瘤化疗患者预期性恶心呕吐干预性研究的现状,为今后的研究提供依据和方向。方法以"预期性恶心呕吐"、"胃肠道反应"、"化疗"为主题词,对中国期刊全文数据库(CNKI)、万方数据库、维普数据库(VIP)及中国生物医学数据库(CBM)关于肿瘤化疗患者预期性恶心呕吐研究的护理文献检索;采用EndNote X3软件查重,对符合纳入排除标准的文献采用改良后的Jadad量表进行方法学质量评价,采用CONSORT声明2010版本对文献报告质量进行综合评价。结果共检索出10篇有关预期性恶心呕吐的干预性研究,干预方法涉及中医护理、心理干预及音乐疗法等。本次纳入的文献方法学质量极低,Jadad评分均低于2分,只有1项研究使用随机数字表进行随机分配,其他文献均只提及"随机"字样;无1篇采用分配隐藏、盲法及失访与退出的报道。纳入研究报告书写欠规范,主要体现在忽视随机方法的阐述、缺乏盲法、分配隐藏的使用、样本量无具体的估算方法、缺乏依从性、病例脱落及失访情况的分析及忽视不良反应的报告等。结论国内有关肿瘤化疗患者预期性恶心呕吐干预性研究较少;文献方法学质量较差,报告书写欠规范,因此,应加强预期性恶心呕吐干预性研究的方法学研究,注重报告的书写规范,以提高科研质量,满足循证需求。
Objective To analyze the current intervention studies on anticipatory nausea and vomiting for cancer patients with chemotherapy and to provide reference for its future studies in China. Methods Literature review with anticipatory nausea and vomiting, gastrointestinal reaction and chemotherapy as key words was conducted in CNKI, Wanfang Data, VIP and CBM and EndNote X3 was applied for duplicate checking, improved Jadad score for methodological quality assessment for those included then comprehensive assessment of the literatures was formed through The CONSORT （Consolidated Standards of Reporting Trials） 2010 Statement. Results Ten literatures were included and interventions mentioned in the literatures involved TCM nursing, psychological intervention and music therapy. Average Jadad score of the literatures was less than two, which indicated poor quality of the literatures. Random number table was found in only one literature and no literature reporting the results with allocation concealment, blinding and withdraw/lost follow-up was found and all literatures lacked standardized writing. Conclusion With poor methodology quality and non-standardized writing, there are less intervention studies on anticipatory nausea and vomiting for cancer patients with chemotherapy in China. Methodology studies on anticipatory nausea and vomiting are in urgent need and more attention should be paid to standardized writing.
出处
《护理学报》
2014年第14期1-4,共4页
Journal of Nursing（China）
基金
江苏省国家中医临床研究基地(脾胃病)开放课题(JD110442)
江苏省高校优势学科建设工程项目
南京中医药大学护理学一级学科开放基金课题(YSHL0101-04)
江苏省中医院院级课题
关键词
恶心呕吐
预期性
化疗
文献分析
anticipatory nausea and vomiting
chemotherapy,literature analysis
