摘要
目的：研究讨论拉莫三嗪与卡马西平分别用于治疗三叉神经痛的临床疗效对比与意义。方法随机选取我院神经内科确诊为三叉神经痛患者100例。根据随机分组原则分为A、B两组，A组50例患者使用拉莫三嗪进行治疗，B组50例患者使用卡马西平治疗。比较两组患者治疗后总有效率及治疗后1～2个月VAS评分等指标。结果两组患者治疗总有效率比较显示使用拉莫三嗪治疗患者总有效率（90％）显著高于使用卡马西平患者（82％），P＜0.05。 VAS评分人数比较显示拉莫三嗪组患者其评分指标人数显著优于使用卡马西平组患者（ P＜0.05）。结论临床应用拉莫三嗪与卡马西平治疗三叉神经痛均有显著疗效。拉莫三嗪作为新型抗癫痫药物对于疾病治疗效果更好，其短期疗效显著，服药后不良反应较少，值得临床广泛推广使用。
Objective To discuss the clinical effect comparison and significance of lamotrigine and carbamazepine for treatment of prosopalgia.Methods 100patientswithprosopalgiawererandomlychosenanddividedintoAandBgroup,with50casesineachgroup.A group was given lamotrigine for treatment while B group was given karbamazepine.Total effective rates and VAS scores after 1 to 2 months treatment of the 2 groups were compared.Results Total effective rate of A group , which was 90%obviously higher than B group 82.0%（ P〈0.05 ）;VAS scores of patients of A group were obviously higher than B group （ P〈0.05 ）.Conclusion Both lamotrigine and car-bamazepine have obvious clinical effect for treatment of prosopalgia.Lamotrigine as a new antiepileptic drug has better clinical effect for the diseases.
出处
《黑龙江医学》
2014年第7期798-799,共2页
Heilongjiang Medical Journal
