摘要
目的对乌司他丁在治疗急性胰腺炎时对急性胰腺炎相关性肺损伤的治疗作用。方法选取2012年6月至2013年6月入我院接受治疗的急性胰腺炎合并急性胰腺炎相关性肺损伤患者80例,将其随机分为观察组与对照组。观察组与对照组人数均为40例。观察组使用常规治疗方式合并乌司他丁进行治疗;对照组使用常规治疗方式。在治疗过程中对患者的呼吸频率、血气分析结果、胸片变化等情况进行对比分析。结果在接受治疗的阶段中观察组患者的肺损伤程度明显低于对照组,存在显著差异,具有统计学意义,P<0.05。并且观察组患者出现急性呼吸窘迫综合征与多脏器功能障碍综合征的出现率低于对照组,死亡率也明显下降,P<0.05。结论乌司他丁在治疗急性胰腺炎合并急性胰腺炎相关性肺损伤时疗效明显,可以显著降低炎症反应,并降低死亡率。
Objective To analyze the therapeutic effect of Ulinastatin in the treatment of acute pancreatitis acute pancreatitis associated lung injury. Methods June 2012 to June 2013 into the hospital for treatment of acute pancreatitis with acute pancreatitis associated lung injury 80 patients were randomly divided into observation group and control group. The number of observation group and control group were 40 cases each. Observation group used conventional treatment combined ulinastatin treatment, the control group using conventional treatment. In the course of treatment the patient's respiratory rate,blood gas analysis ,etc. ray changes wereanalyzed. Results The degree of lung damage in treated patients was observed phase was significantly lower than that of the control group,there were significant differences,with statistical significance,P 〈 0. 05. And observing patients with acute respiratory distress syndrome occurrence rate of multiple organ dysfunction syndrome than the control group,the mortality rate also decreased significantly,P 〈 0. 05. Conclusion Ulinastatin in the treatment of acute pancreatitis with acute pancreatitis associated lung injury significant effect ,can significantly reduce inflammation and reduce mortality.
出处
《医药论坛杂志》
2014年第6期6-8,12,共4页
Journal of Medical Forum
基金
河南省医学科技攻关计划项目(20130366)
关键词
乌司他丁
急性胰腺炎
临床疗效
Ulinastatin
Acute pancreatitis
Clinical efficacy