摘要
目的探讨参附注射液对急性心肌梗死合并泵衰竭患者超声心动图的影响及临床疗效。方法选取急性心肌梗死合并泵衰竭患者80例，按随机数字表法分为对照组和试验组，每组40例，对照组给予常规药物治疗，试验组在常规药物治疗基础上加用参附注射液，比较两组患者治疗后的临床疗效及超声心动图变化。结果试验组总有效率显著高于对照组[82．5％（33／40）比50．0％（20／40）]，差异有统计学意义（P〈0．05）。超声心动图检查示，两组患者治疗前E峰速度、左室射血分数、左室短轴缩短率、E／A比较差异无统计学意义（P〉0．05），治疗后均较治疗前显著改善，且试验组改善情况优于对照组[（0．87±0．18）m／s比（0．65±0．22）m／s、（51．0±10．2）％比（43．9±12．1）％、（27．5±6．5）％比（22．5±5．3）％、0．86±0．18比0．76±0．13]，差异有统计学意义（P〈0．05）。结论应用参附注射液治疗急性心肌梗死合并泵衰竭，可有效改善预后，降低病死率，有良好的临床价值。
Objective To study the clinical effect of shenfu injection on ultrasound cardiogram in patients of acute myocardial infarction combined with pump failure. Methods Eighty patients with acute myocardial infarction combined with pump failure were divided into control group and experiment group by random digits table method with 40 cases each. The patients in control group received common drug treatment,and the patients in experiment group received common drug combined with shenfu injection treatment. The clinical effect and the change of ultrasound cardiogram after treatment were compared between the 2 groups. Results The total effective rate in experiment group was significantly higher than that in control group [82.5% （33/40） vs. 50.0% （20/40）], and there was statistical difference （P 〈 0.05）. The results of ultrasound cardiogram showed there were no statistical differences in peak E velocity, left ventricular ejection fraction,left ventricular fractional shortening and E/A before treatment between the 2 groups （P 〉 0.05）, and the indexes were significantly improved after treatment compared with those before treatment. Furthermore, the indexes in experiment group were significantly better than those in control group [ （0.87± 0.18） m/s vs. （0.65 ± 0.22） m/s, （51.0 ± 10.2）% vs. （43.9±12.1 ）%, （27.5 ± 6.5）% vs. （22.5± 5.3）%, 0.86 ~0.18 vs. 0.76±0.13],and there were statistical differences （P 〈0.05）. Conclusion Shenfu injection may play an important role in improving prognosis,decreasing mortality for patients with acute myocardial infarction combined with pump failure.
出处
《中国医师进修杂志》
2014年第19期56-58,63,共4页
Chinese Journal of Postgraduates of Medicine
关键词
心肌梗死
参附注射液
泵衰竭
Myocardial infarction
Shenfu injection
Pump failure
