摘要
目的 :观察血府逐瘀汤对全身炎症反应综合征 (SIRS)患者氧自由基的影响。方法 :34例 SIRS患者随机分为常规治疗组 (18例 )和血府逐瘀汤 +常规治疗组 (16例 ) ,所得结果进行治疗前后自身比较及组间对照比较。结果 :治疗后血清超氧化物歧化酶 (SOD)、全血谷胱甘肽过氧化物酶 (GSH Px)活性明显高于治疗前 (P<0 .0 1) ,血浆过氧化脂质 (L PO)则低于治疗前 (P<0 .0 1) ,组间对照比较也存在显著性差异。结论 :采用血府逐瘀汤结合常规西医治疗能提高机体细胞抗氧化酶的活性 ,降低脂质过氧化 ,在一定程度上能阻止炎症反应进一步发展 ,对 SIRS患者起到了一定的治疗作用。
Objective:To observe the effects of Xuefuzhuyu decoction(血府逐瘀汤)on oxygen free radicals in patients with systemic inflammatory response syndrome(SIRS).Methods:Thirtyfour SIRS cases were divided randomly into 2 groups.The control group(18 cases) was treated with conventional therapy and the treatment group (16 cases) was treated with conventional therapy combining Xuefuzhuyu decoction.Results:The patients in treatment group who were treated with Xuefuzhuyu decoction had more marked effects than those in control group.After treatment,the serum superoxide dismutase(SOD) and blood glutathione peroxidase(GSHPx) elevated significantly,and plasma lipid peroxide(LPO) content decreased significantly in treatment group than those before treatment and those in control group after treatment.Conclusions:It suggested that Xuefuzhuyu decoction may have the effects in preventing the SIRS from happening and it can enhance antioxidation activity and attenuate lipid peroxide reaction.
出处
《中国中西医结合急救杂志》
CAS
2002年第4期228-229,共2页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
血府逐瘀汤
全身炎症反应综合征
抗氧化酶
氧自由基
炎性介质
Xuefuzhuyu decoction
systemic inflammatory response syndrome
antioxidation
oxygen free radicals
inflammation mediators
