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子宫内膜异位症异位内膜IL-6基因表达的研究 被引量:3

A study of interleukin-6 gene expression on ectopic endometrium in endometriosis
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摘要 目的 探讨子宫内膜异位症 (内异症 )异位内膜白细胞介素 6 (IL 6 )mRNA表达的变化。方法 利用大鼠内异症动物模型 ,采用逆转录聚合酶链反应 (RT PCR)技术 ,检测子宫内膜IL 6mRNA表达情况。结果 正常对照组、内异症模型组在位及异位子宫内膜IL 6mRNA的表达明显不同 ,内异症异位子宫内膜的表达高于内异症在位子宫内膜 ;正常子宫内膜IL 6mRNA的表达较前两者均低。同一时间点各组间比较差异具有显著性意义 (P <0 0 1)。结论 内异症异位内膜IL Objective The purpose of our study was to explore the expression of interleukin 6 (IL 6) mRNA in ectopic endometrium with endometriosis. Method Using the rat model of experimental endometriosis,the endometrium was examined by RT PCR.Results The expression of IL 6 mRNA in eutopic endometrium with endometriosis was lower than in endometriotic tissue, but higher than in endometrium from healthy controls(P<0 01). Conclusion The expression level of IL 6 mRNA is high in endometriotic tissue.
出处 《解剖学研究》 CAS 2002年第2期105-107,I002,共4页 Anatomy Research
关键词 子宫内膜异位症 异位内膜 白细胞介素-6 基因表达 Endometriosis Ectopic endometrium Interleukin 6 Gene expression
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