期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

维生素D与糖尿病肾病 被引量：6

下载PDF
导出
摘要 糖尿病是以糖代谢紊乱为主要表现的临床综合征,是由环境因素和遗传因素共同作用所致。长期的高血糖状态可引起多个器官的慢性并发症,其中糖尿病肾病是最严重的并发症之一,目前尚无有效的预防和干预手段,有必要通过研究寻找新的防治方法。近年来研究[1]表明维生素D缺乏是慢性肾脏病的重要特征,具有激素活性的维生素D3亦显示出具有肾脏保护作用。本文将对维生素D与维生素D受体(vitamin drecep-
作者 刘燕 戴武
机构地区 安徽医科大学附属合肥医院(合肥市第二人民医院)广德路院区内分泌科
出处 《安徽医学》 2015年第12期1552-1554,共3页 Anhui Medical Journal
基金 合肥市科技局重点立项课题(合科2013[183号])
关键词 25-羟维生素D 糖尿病肾病
分类号 R587.2 [医药卫生—内分泌]
  • 相关文献

参考文献25

  • 1Bonakdaran Shokoufeh,Hami Maryam,Hatefi Asieh.The effects of calcitriol on albuminuria in patients with type-2 diabetes mellitus. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia . 2012 被引量：1
  • 2Yuan, Weihua,Pan, Wei,Kong, Juan,Zheng, Wei,Szeto, Frances L.,Wong, Kari E.,Cohen, Ronald,Klopot, Anna,Zhang, Zhongyi,Yan, Chun Li.1,25-Dihydroxyvitamin D 3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. Journal of Biological Chemistry . 2007 被引量：1
  • 3Kuhlmann Alexander,Haas Christian S,Gross Marie-Luise,Reulbach Udo,Holzinger Marc,Schwarz Ute,Ritz Eberhard,Amann Kerstin.1,25-Dihydroxyvitamin D3 decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat. American journal of physiology. Renal physiology . 2003 被引量：1
  • 4Zhang Z,Yuan W,Sun L,Szeto F L,Wong K E,Li X,Kong J,Li Y C.1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney International . 2007 被引量：1
  • 5Hwang PT,Kwon OD,Kim HJ,et al.Hyperglycemia decreases the expression of ATP synthase|J subunit and enolase 2 in glomerular epithelial cells. Tohoku Journal of Experimental Medicine . 2012 被引量：1
  • 6Bikle D.Nonclassic actions of vitamin D. The Journal of Clinical Endocrinology . 2009 被引量：1
  • 7Zhang Zhongyi,Zhang Yan,Ning Gang,Deb Dilip K,Kong Juan,Li Yan Chun.Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proceedings of the National Academy of Sciences of the United States of America . 2008 被引量：1
  • 8Good David W,George Thampi,Watts Bruns A.Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway. American journal of physiology. Cell physiology . 2003 被引量：1
  • 9Bourlon P M,Billaudel B,Faure-Dussert A.Influence of vitamin D3 deficiency and 1,25 dihydroxyvitamin D3 on de novo insulin biosynthesis in the islets of the rat endocrine pancreas. The Journal of Endocrinology . 1998 被引量：1
  • 10Diaz Vanessa A,Mainous Arch G,Carek Peter J,Wessell Andrea M,Everett Charles J.The association of vitamin D deficiency and insufficiency with diabetic nephropathy: implications for health disparities. Journal of the American Board of Family Medicine : JABFM . 2009 被引量：1

二级参考文献67

  • 1Department of Health and Human Services.2011 National Diabetes Fact Sheet[R/OL].[2013-07-22].http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf. 被引量：1
  • 2Luo C,Wong J,Brown M,et al.Hypovitaminosis D in Chinese type 2 diabetes:lack of impact on clinical metabolic status and biomarkers of cellular inflammation.Diab Vasc Dis Res,2009,6:194-199. 被引量：1
  • 3Tahrani AA,Ball A,Shepherd L,et al.The prevalence of vitamin D abnormalities in South Asians with type 2 diabetes mellitus in the UK.Int J Clin Pract,2010,64:351-355. 被引量：1
  • 4Pittas AG,Lau J,Hu FB,et al.The role of vitamin D and calcium in type 2 diabetes.A systematic review and metaanalysis.J Clin Endocrinol Metab,2007,92:2017-2029. 被引量：1
  • 5Diaz VA,Mainous AG 3rd,Carek PJ,et al.The association of vitamin D deficiency and insufficiency with diabetic nephropathy:implications for health disparities.J Am Board Fam Med,2009,22:521-527. 被引量：1
  • 6Plum LA,Zella JB.Vitamin D compounds and diabeticnephropathy.Arch Biochem Biophys,2012,523:87-94. 被引量：1
  • 7Levin A,Bakris GL,Molitch M,et al.Prevalence of abnormal serum vitamin D,PTH,calcium,and phosphorus in patients with chronic kidney disease:results of the study to evaluate early kidney disease.Kidney Int,2007,71:31-38. 被引量：1
  • 8Thrailkill KM,Jo CH,Cockrell GE,et al.Enhanced excretion of vitamin D binding protein in type 1 diabetes:a role in vitamin D deficiency?.J Clin Endocrinol Metab,2011,96:142-149. 被引量：1
  • 9Thrailkill KM,Nimmo T,Bunu RC,et al.Microalbuminuria in type 1 diabetes is associated with enhanced excretion of the endocytic multiligand receptors megalin and cubilin.Diabetes Care,2009,32:1266-1268. 被引量：1
  • 10Sonneveld R,Ferrè S,Hoenderop JG,et al.Vitamin D downregulates TRPC6 expression in podocyte injury and proteinuric glomerular disease.Am J Pathol,2013,182:1196-1204. 被引量：1

共引文献59

同被引文献59

  • 1陆燕,黄高忠.维生素D与老年认知功能障碍相关性的研究进展[J].中华临床医师杂志（电子版）,2011,5(19):5725-5728. 被引量：8
  • 2彭丹涛,许贤豪,刘江红,矫玉娟,张华,殷剑,孟晓梅,谢琰臣,冯凯.简易智能精神状态检查量表检测老年期痴呆患者的应用探讨[J].中国神经免疫学和神经病学杂志,2005,12(4):187-190. 被引量：149
  • 3Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25- hydroxyvitamin D status: a systematic review and meta-analysis [J]. Am J Clin Nutr,2012,95(6):1357-1364. 被引量：1
  • 4Meehan M, Penckofer S. The role of vitamin D in the aging adult[J]. J Aging Gerontol,2014,2(2) :60-71. 被引量：1
  • 5Gonzalez-Parra E, Rojas-Rivera J, Tunon J, et al. Vitamin D receptor activation and cardiovascular disease[J]. Nephrol Dial Transplant, 2012,27 Suppl 4: ivl 7-21. 被引量：1
  • 6Carlberg C, Campbell MJ. Vitamin D receptor signaling mechanisms integrated actions of a well-defined transcription factor[-J~. Steroids, 2013,78(2) : 127-136. 被引量：1
  • 7Brondum-Jacobsen P, Nordestgaard BG, Schnohr P, et al. 25- Hydroxyvitamin D and symptomatic ischemic stroke: an original study and meta-analysis[J]. Ann Neurol, 2013,73 (1), 38-47. 被引量：1
  • 8Sun Q, Pan A, Hu FB, et al. 25-Hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis[J]. Stroke, 2012,43(6) : 1470-1477. 被引量：1
  • 9Chowdhury R, Stevens S, Ward H, et al. Circulating vitamin D, calcium and risk of eerebrovascular disease: a systematic review and meta-analysis[J].Eur J Epidcmiol, 2012,27 (8) : 581- 591. 被引量：1
  • 10Daubail B, Jaequin A, Guilland JC, et al. Serum 25- hydroxyvitamin D predicts severity and prognosis in stroke patients[J]. Eur J Neurol,2013,20(1) :57-61. 被引量：1

引证文献6

二级引证文献74

安徽医学
2015年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部