摘要
目的分析心房颤动患者的影响因素,为制定相关干预措施提供科学依据。方法选取住院治疗资料完整的心房颤动患者作为病例组,并随机从同时期在心内科接受治疗的其他非心房颤动患者中选取同等数量作为对照组进行非匹配的病例对照研究,采用多因素非条件logistic回归方法分析心房颤动的影响因素。结果共有效调查556例患者,其中病例组和对照组分别为278例。多因素分析结果显示,年龄增加(OR=1.037,95%CI:1.022~1.052)、高血压(OR=2.395,95%CI:1.361~4.214)、糖尿病(OR=2.374,95%CI:1.301~4.333)、冠心病(OR=2.620,95%CI:1.480~4.638)、心脏病(OR=3.468,95%CI:1.834~6.560)、心力衰竭(OR=3.050,95%CI:1.741~5.345)、尿酸增加(OR=1.011,95%CI:1.005~1.016)、左房内径增加(OR=1.201,95%CI:1.130~1.276)是房颤的危险因素;女性(OR=0.518,95%CI:0.321~0.837)、左室射血分数(OR=0.097,95%CI:0.021~0.449)、三酰甘油(OR=0.418,95%CI:0.252~0.693)、高密度脂蛋白(OR=0.381,95%CI:0.213~0.683)以及低密度脂蛋白水平增加(OR=0.230,95%CI:0.127~0.417)是房颤的保护因素。结论很多因素可以影响心房颤动的发生,相关部门应该从多方面制定综合的心房颤动预防控制措施。
Objective To investigate the influence factors of atrial fibrillation to provide a scientific basis for the government to make the intervention measures. Methods The patients of atrial fibrillation who had complete information and were hospitalized in department of cardiology of Lu’an People’s Hospital from January to May,2014 were viewed as case group. The other patients who did not have atrial fibrillation and were hospitalized in department of cardiology in the same period were randomly selected as the control group. The non-matching casecontrol study and unconditioned multivariate logistic regression were used to analyze the relative factors of atrial fibrillation. Results A total of 556 participants( number of case group and control group was 278,278,respectively) were included in this analysis. The elder age( OR =1. 037,95% CI: 1. 022 ~ 1. 052),hypertension( OR = 2. 395,95% CI: 1. 361 ~ 4. 214),diabetes( OR = 2. 374,95% CI: 1. 301 ~ 4. 333),coronary heart disease( OR = 2. 620,95% CI: 1. 480 ~ 4. 638),heart disease( OR = 3. 468,95% CI: 1. 834 ~ 6. 560),heart failure( OR =3. 050,95% CI: 1. 741 ~ 5. 345),increased uric acid( OR = 1. 011,95% CI: 1. 005 ~ 1. 016),and increased left atrial diameter( OR =1. 201,95% CI: 1. 130 ~ 1. 276) were risk factors for atrial fibrillation; women( OR = 0. 518,95% CI: 0. 321 ~ 0. 837),an increased level of left ventricular ejection fraction( OR = 0. 097,95% CI: 0. 021 ~ 0. 449),triglycerides( OR = 0. 418,95% CI: 0. 252 ~ 0. 693),high density lipoprotein( OR = 0. 381,95% CI: 0. 213 ~ 0. 683) and low density lipoprotein( OR = 0. 230,95% CI: 0. 127 ~ 0. 417) were the protective factors for atrial fibrillation. Conclusion Many factors can affect the atrial fibrillation,therefore,relevant departments should make comprehensive intervention measures for atrial fibrillation.
出处
《安徽医学》
2015年第1期45-48,共4页
Anhui Medical Journal
关键词
心房颤动
影响因素
非匹配
病例对照研究
Atrial fibrillation
Influence factor
Non-matching
Case-control study
