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血糖水平对急性冠脉综合征患者住院期间短期预后影响的临床观察 被引量:3

Influence of glucose levels on prognosis of patients with acute coronary syndrome
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摘要 目的分析急性冠脉综合征(ACS)患者入院血糖水平对预后的影响。方法选择无糖尿病史的ACS患者110例,分为不稳定型心绞痛(UA)55例,非ST段抬高心肌梗死组(NSTEMI)25例,ST段抬高心肌梗死组(STEMI)30例。分别测各组发病后入院时随机末梢血糖以及第2 d空腹血糖,记录患者血糖水平及其在住院期间发生的主要心血管不良事件(MACE),包括心力衰竭、恶性心律失常和心源性死亡。结果 UA组空腹血糖异常的发生率和平均空腹血糖水平在3组中均最低,NSTEMI组居中,STEMI组最高,差异有统计学意义(P<0.05);同时发现血糖最高的STEMI组MACE发生率明显升高,差异有统计学意义(P<0.05)。结论 ACS的危险程度与血糖水平程度以及血糖异常的发生率呈正相关,高血糖是ACS患者独立的危险因素。 Objective To analyse the effect of glucose levels on the prognosis of hospitalized patients with acute coronary syndrome. Methods A total of 1 1 0 patients with acute coronary syndrome and with non-diabetic history were chosen and divided into 3 groups,namely unstable angina (UA)with 55 patients,non-ST-segment elevation myocardial infarction (NSTEMI)with 25 cases,and ST segment elevation myocardial infarction (STEMI)with 30 cases.Random peripheral blood glucose after the onset of disease in admission to hospital and the next day random fasting blood glucose were measured,and the incidence of abnormal glucose levels and blood sugar,and major adverse cardiac e-vent (MACE)during hospitalization were observed,including heart failure,malignant arrhythmias,and cardiac death.Results The incidence of abnormal fasting glucose and mean fasting blood glucose levels in UA group were the lowest among the three groups,they were in the middle in NSTEMI group,and the highest STEMI group.The difference among the three groups were statistically significant(P<0.05 );it was also found that MACE rates were significantly increased in STEMI group with the highest blood sugar,and the difference was statistically significant (P<0.05).Conclusion The degree of risk for acute coronary syndrome is positively correlated with glucose levels and glucose abnormali-ties,which is an independent risk factor for acute coronary syndrome in patients.
出处 《安徽医学》 2014年第6期758-760,共3页 Anhui Medical Journal
关键词 急性冠脉综合征 预后 高血糖 Acute coronary syndrome Prognosis Hyperglycemia
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