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全直肠系膜切除直肠癌根治术后局部复发78例的临床观察 被引量:8

Local recurrence after radical resection with total mesentery excision (TME) for the treatment of rectal cancer
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摘要 目的探讨全直肠系膜切除 (TME)在预防直肠癌根治术后局部复发的临床效果。方法对 78例直肠癌患者在根治术中施行TME ,并对全组病例随访 5年。结果 78例均随访 5年以上。 5年间共有 10例局部复发 ,复发率为 13% (10 /78) ,其中 7例在二年内复发。局部复发与肿瘤病理性质和Dukes分期有明显关系。恶性度越高复发率越高 ,分期越晚复发率越高。TME直肠癌根治术后 5年局部复发率明显低于普通术式 ,生存期超过 5年的有 6 9例 ,5年生存率达 88% (6 9/78) ,Dukes分期A、B、C的 5年存活率分别为 10 0 % (9/9)、92 % (5 1/5 4 )和 6 4 % (9/14 )。结论TME是预防直肠癌术后局部复发的有效措施 ,值得推广。 ObjectiveTo evaluate the effect of radical proctectomy with TME for the treatment of rectal carcinoma in the prevention of postoperative local recurrence. Method78 patients undergoing this procedure were followed up for 5 years.ResultLocal recurrence developed in 10 cases during 5 year′s follow up, with recurrence related mortality of 7/78, local recurrence rate of 10/78 (13%). Tumor malignancy and Dukes′ grade were in direct proportion with the recurrence. The 5 year′s survival rate was 88%(69/78). The postoperative 5 year′s survival rate in Dukes′ A, B and C patients was respectively 100%(9/9), 92%(51/54), and 64%(9/14). ConclusionRadical proctectomy with TME is superior to that without TME in terms of low postoperative local recurrence rate for the treatment of rectal carcinoma.
出处 《中华普通外科杂志》 CSCD 北大核心 2002年第7期398-400,共3页 Chinese Journal of General Surgery
关键词 结肠直肠肿瘤 局部肿瘤复发 肠系膜 外科手术 治疗 Colorectal neoplasms Neoplasm recurrence, local Mensentery Surgical procedures, operative
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