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吲哒帕胺致老年低血钾3例 被引量:7

Three patients with hypokalemia caused by indapamide
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摘要 报道 3例分别被诊断为食道裂孔疝、脑震荡后遗症、冠心病和频发室性期前收缩的老年高血压病人服用吲哒帕胺引起的低血钾。认为引起低血钾的原因是与老年人体内含钾量低、多病并存和器官的退行性变有关。原发或伴随疾病症状的掩盖 ,使诊断较为困难。提高对老年人病理生理及用药特点的认识 ,详细询问病史、用药史 ,多吃含钾较高的食物 ,或与氯化钾片、保钾利尿剂同时服用 ,多药合用时注意协同排钾作用 ,定期复查血钾等 ,是预防吲哒帕胺致老年低血钾的主要措施。 It is reported that three patients with hypokalemia of geriatric hypertensive patients who has been diagnosed respectively as “Esophageal hiatus hernia”, “postconcussional syndrome” and “coronary heart disease, frequently ventricular premature beats” caused by taking indapamide. It was regarded that this related to low potassium content, various diseases coexisted, and degeneration of organs in old people. Because of being covered by symptoms of primary or followed diseases, the diagnosis became more difficult. Five capital measures can be used to prevent from geriatric hypokalemia caused by indapamide: (1) To promote the cognition of old people's pathophysiology and characteristic medication; (2) To ask detail about medical history and medicine history; (3) To eat lots of foods which contain high potassium level or take potassium chloride tablet and potassium sparing diuretic simultaneously when takes indapamide; (4) To pay much attention to synergy of discharging potassium when combining to use several kinds of medicines; (5) To carry out periodic reexamination.
作者 王建群
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2002年第7期442-444,共3页 Chinese Journal of New Drugs and Clinical Remedies
关键词 药源性疾病 吲哒帕胺 老年人 低钾血症 indapamide aged hypokalemia
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