摘要
目的 探讨Dubin Johnson综合征的临床病理特征、诊断及鉴别诊断。方法 收集 4例临床病理资料 ,切片作常规HE染色及特殊染色 ,镜下观察。结果 肝细胞内见大量棕黄色色素存在 ,脂褐素染色阳性 ,黑色素染色阴性 ,含铁血黄素染色阴性 ,部分病例胆色素染色阳性。结论 Dubin Johnson综合征是一种良性病变过程 ,肝细胞内的色素可合并胆色素存在 。
Objective To study the clinical pathological characteristics and the diagnosis and differential diagnosis of the Dubin-Johnson syndrome. Methods Hematoxylin-eosin and histochemical stains were performed in paraffin-embedded tissue sections from 4 cases of the Dubin-Johnson syndrome. Results There were a great deal of brown pigment in liver cells. Lipofuscin staining showed positive reaction, but melanin staining was negative.Haemosiderin staining showed negative reaction and bile pigment was positive in some cases. Conclusions Dubin-Johnson syndrome is a benign pathological process.The brown pigment is present together with bile pigment in liver cells. It differs from bile deposition of other jaundice in the liver.
出处
《诊断病理学杂志》
CSCD
2002年第3期149-150,T041,共3页
Chinese Journal of Diagnostic Pathology
