摘要
目的 :随访经皮二尖瓣球囊成形术 (PBMV)治疗风湿性二尖瓣狭窄长期疗效。方法 :采用 Inoue单球囊扩张狭窄的二尖瓣 ,对 PBMV术患者 2 2 7例进行追踪随访 ,评价临床心功能和瓣口状况。平均随访时间 (6 .3± 2 .1)年。结果 :PBMV术后二尖瓣口面积 (MVA )显著扩大 ,从 (1.0 1± 0 .2 8) cm 2扩至 (2 .34± 0 .17) cm2 (P<0 .0 1) ,长期随访 ,MVA逐渐减小至 (1.6 6± 0 .37) cm2 (P<0 .0 1)。再狭窄率为 2 2 .9%。二尖瓣跨瓣压差 (MVG)从 (19.5± 6 .2 )mm Hg分别减少至术后、随访的 (7.4± 5 .1)和 (10 .1± 4.9) m m Hg,差别显著 (P<0 .0 1)。随访中临床心功能改善仍然维持 1个级别以上者达 77.1%。随访射血分数 (EF)变化不大、二尖瓣返流 (MR)较术前、后明显加重 (P<0 .0 1)。结论
AIM: To evaluate the long-term outcome of percutaneous balloon mitral valvuloplasty (PBMV). METHODS: 227 patients with rheumatic mitral stenosis underwent PBMV with the Inoue balloon catheter for a follow-up (FU) period of 6.3±2.1 years. The clinical status and echocardiographic variables were assessed. RESULTS: The mitral valve areas after PBMV and FU were significantly larger than that before PBMV (planimetry 2.34±0.17 cm 2, 1.66±0.37 cm 2 vs 1.01±0.28 cm 2, respectively, P<0.01). The restenosis rate at the end of the follow-up period was 22.9%. The mean transmitral valve gradients after PBMV and FU were significantly less than that before PBMV (7.4±5.1 mm Hg, 10.1±4.9 mm Hg vs 19.5±6.2 mm Hg, respectively, P<0.01). Functional status still improved above one class (NYHA) was 77.1% of patients at FU. Ejection fraction had not obvious difference. Mitral regurgitation at FU was significantly than at pre- or post-PBMV, P<0.01. CONCLUSION: PBMV is effective therapy with good long-term results for selected patients with mitral stenosis.
出处
《心脏杂志》
CAS
2002年第3期232-234,共3页
Chinese Heart Journal
关键词
二尖瓣狭窄
球囊扩张术
随访
mitral valve stenosis
balloon dilatation
follow-up studies
