摘要
以Na2S2为还原剂,将4-硝基-4＇-氯二苯甲酮还原成4-氨基-4’-氯二苯甲酮,通过对反应物配比、反应时间、反应温度进行多因素正交试验,确定了最佳工艺条件,反应温度92℃,反应时间2.5小时,4-硝基-4＇-氯二苯甲酮:Na2S2=1∶1.7（mol）,收率为85.80％,含量为98.08％。产品结构经红外光谱、核磁共振、质谱和元素分析证实。实验操作简单,分离容易。
4-Amino-4'-chlorobenzophenone was prepared by reduction of 4-nitro-4'-chlorobenzophenone with Na2S2. With the aid of orthogonal experiments the optimum reaction conditions were determined: reaction temperature 92℃, time 2.5hrs, 4-nitro-4'-chlorobenzophenone: Na2S2=1:1.7(mol), yield 85.80%, m.p.177℃-179℃. the structure of the product was confirmed by m.p., IR,NMR and EMA spectra. Simple operation and easy separation of the products were claimed.
出处
《染料工业》
CAS
2002年第3期28-29,共2页
Dyestuff Industry
