摘要
通过核磁共振磷谱对克林霉素磷酸酯合成反应过程进行跟踪 ,尤其是对克林霉素一氯代磷酸酯的水解情况进行了较为细致的分析 ,了解了反应中的一些机理问题 。
In this paper the process of synthesizing clindamycin has been observed by \{\}\+\{31\}P NMR, especially, the hydrolyzing reaction form of clindamycin phosphate chloride was investigated. And some reaction mechanism has been discussed. The rational reaction condition was obtained by the study.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2002年第2期181-186,共6页
Chinese Journal of Magnetic Resonance
基金
河南省自然科学基金资助项目 (0 0 40 3 2 0 0 0 )
