摘要
目的 :比较直接经皮冠状动脉腔内成形术 (PTCA)与静脉溶栓治疗急性心肌梗塞 (AMI)的疗效。方法 :96例AMI患者 ,53例接受静脉溶栓治疗 ,43例接受直接PTCA治疗。结果 :溶栓治疗组梗塞相关血管 (IRA)再通率为 64 .1 % ,直接PTCA组的IRA开通率为 93 .0 % ,溶栓组存活患者的LVEF为 (53 .9± 9.4) % ,急诊PTCA组为 (59.4± 1 1 .2 ) % ,两组差异显著 (P <0 .0 5)。两组的病死率分别为 1 5 .1 % (8/ 53)和 7.0 % (3/ 4 3) ,两组差异无显著性 (P >0 .0 5)。溶栓组出血发生率和出血程度较直接PTCA组严重 ,而且心脏破裂的机会增多 ,但无显著差异 (P >0 .0 5)。结论 :直接PTCA治疗AMI可以更加安全、充分有效地开放IRA ,保存心脏功能。
Objective:To compare the clinical efficacy of primary angioplasty with thrombolytic therapy in the treatment of acute myocardial infarction (AMI).Methods:Ninety_six consecutive patients with AMI underwent either intravenous thrombolytic therapy (53 patients) or primary angioplasty (43 patients).Cardiac function (left ventricular ejection fraction,LVEF) was assessed during hospitalization by echocardiography.Results:The recanalizing rate of infarct related artery (IRA) in patients with thrombolytic therapy was 64.1%,while in those with primary angioplasty was 93.0%.There were no significant differences in age,risk factors,time from onset of symptom to hospital presentation between these two,but apparent differences were found in LVEF (53.9±9.4 vs 59.4±11.2, P <0.05).Conclusions:This study showed that primary PTCA is more effective than thrombolytic therapy in preserving cardiac function after AMI.
出处
《中国现代医学杂志》
CAS
CSCD
2002年第5期16-19,共4页
China Journal of Modern Medicine
