摘要
目的 :探讨梗阻性黄疸发生急性肾功能损害时的相关高危因素。方法 :对 15 0例梗阻性黄疸患者中 9例发生急性肾功能损害的临床情况进行分析。结果 :年龄、术前胆红素水平、肝功能异常与梗阻性黄疸(OJ)引发的急性肾功能损害无明显相关性 (P >0 .0 5 ) ;而围手术期较长时间的低血压状态、发病时胆道感染状况以及既往手术史与梗阻性黄疸 (OJ)引发的急性肾功能损害 (ARI)有显著相关性 (P <0 .0 1)。结论 :OJ时的胆道感染、围手术期较长时间的低血压状态及既往手术史 ,与ARI的发生有较为密切的关系 ;而单纯的高胆红素血症在OJ引发的ARI中的作用有限。
Objective:The purpose of this study was to investigate the dangerous factors associated with the development of acute renal impairment in patients with obstructive jaundice.Methods:An analysis of 150 patients with obstructive jaundice had been made since 1994. Nine patients developed acute renal impairment. The two groups of patients were initially compared by the standard univariate statistical tests(χ 2,t tests) to identify the data significantly associated with the development of acute renal impairment. Stepwise logistic regression analysis was then performed on these data with SAS Statistical Package.Results:There was no significant association between acute renal impairment and ages,preoperative serum bilirubin,and abnormal liver function(P>0.05),but great association between acute renal impairment and longer hypertension during perioperation,pre operative evidence of infection and previous biliary surgery(P<0.01).Conclusion:Longer hypertension during perioperation,preoperative evidence of biliary infection and previous biliary surgery are dangerous factors in patients with obstructive jaundice,which will come to acute renal impairment.
出处
《肝胆胰外科杂志》
CAS
2002年第1期40-42,共3页
Journal of Hepatopancreatobiliary Surgery
关键词
胆管阻塞
肝外
急性肾功能损害
相关高危因素
bile duct obstruction,extrahepatic
acute renal impairment
dangerous factors
