摘要
目的 分析与肝移植术后早期死亡率有密切关系的术前危险因素。方法 回顾性地收集 5 0例成人肝移植病人的临床和实验室资料 ,对 2 0种待筛选的术前危险因素与术后早期死亡率的关系进行多元回归分析。结果 经单因素和Logistic多元回归分析最终筛选出术前感染情况、急性生理 ,年龄和慢性健康 (APACHE)Ⅲ评分和血浆肌酐 (Cr)水平与术后早期死亡率有独立相关性。经受试者运算特征 (ROC)曲线分析 ,APACHEⅢ的截断点为 6 0分 ,Cr的截断点为 14 0 μmol/L。 结论 术前APACHEⅢ≥ 6 0分、Cr水平≥ 14 0 μmol/L及术前存在感染灶 ,是肝移植受体的术前危险因素 。
Objective To determine preoperative risk factors being related to early mortality after liver transplantation. Methods Clinical and laboratory data of 50 patients underwent liver transplantation were retrospectively analyzed. The relationship between the 20 possible preoperative risk factors and early mortality after orthotopic liver transplantation was investigated using logistic regression. Results Amongst the 20 possible risk factors, only cute physiology, age and chronic health evaluation (APACHE Ⅲ) scores, history of infection and preoperative serum creatinine level had a significant independent association with early mortality. The examination of the receiver operating characteristics (ROC) curve showed that the cutpoints of APACHE Ⅲ score and serum creatinine were 60 points and 140 μmol/L. Conclusions The outcome is poor if a patient has an existence of infection, APACHE Ⅲ score ≥60 and/or serum creatinine ≥140 μmol/L.
出处
《中华肝胆外科杂志》
CAS
CSCD
2002年第5期262-264,共3页
Chinese Journal of Hepatobiliary Surgery
