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应用发光分析技术测定带Cu-IUD大白鼠子宫腔渗出细胞的吞噬活性

Phagocytosis of Infiltrating Cells in Uterine Cavity of Cu-IUD-Wearing Rats by Chemiluminescence Technique
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摘要 本文应用化学发光技术测定了大白鼠带Cu-IUD后,在急性期、慢性期和着床期官腔内渗出细胞的吞噬活性。结果发现:急性期其吞噬活性很活跃,吞噬发光强度在15min时达到峰值(5.8±3.4cps);慢性期吞噬活性仍明显高于对照侧,发光强度持续增强,45min时达1.8±0.8cps;交配后吞噬活性进一步增强,发光强度45min时达4.2±3.1cps,提示带器后宫腔渗出细胞的吞噬活性与IUD的避孕机理有一定关系。 In this study, chemiluminescence (CL) technique was developed to analyse the phagocytosis of infiltrating cells in uterine cavity of rats wearing Cu-IUD in the periods of acute, chronic inflammation and in the term of implantation. In acute period, phagocytosis of infiltrating cells was active, the peak of CL reaching 5.8±3.4cps at 15 min of incubation with opsonizd zymosan, while in chronic period, the phagocytosis was lower, CL being 1.8±0.6 cps at 45 min. However, phagocytosis of infiltrating cells was enhanced in the term of implantation, CL reaching 4.2±3.1 cps at 45 min. The above findings suggest that phagocytosis of infiltrating cells in IUD-wearing uterine cavity is related to the mechanism of contraception of IUD.
出处 《同济医科大学学报》 CAS CSCD 北大核心 1991年第1期35-37,共3页 Acta Universitatis Medicinae Tongji
关键词 避孕 宫内节育器 吞shi作用 chemiluminescence technique intrauterine devices copper phagocytosis contraception
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参考文献1

  • 1诸定寿,王兴翠,刘晓兰,革丽苹,邹爱民,周苏文.雌性大鼠子宫腔内放置不同材料节育器的避孕效果和局部影响[J]北京第二医学院学报,1981(03). 被引量:1

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