摘要
目的 总结我院随访实施TIPSS治疗的 6 5例病例的疗效及经验。方法 6 5例肝硬化和Budd Chiari综合征患者 ,行TIPSS治疗。术前、后测量门脉压力。术后通过超声、食管钡餐随访检查 ,发现分流道狭窄者再次行介入治疗。随访时间为 3个月～ 6年 (平均 18个月 )。结果 术后 3个月、6个月、1年、2年和 3～ 6年再发消化道出血的病例数分别为 :0、2、10、5和 0例。出血的原因为分流道内血栓形成及肉芽组织增生所致狭窄 ,经溶栓、球囊扩张或内支架置入后使多数分流道再通。再通未成功的2例均因导丝不能通过分流道而行内科治疗。死亡 7例 ,其中 2例死于大出血 ,1例死于其他原因 ,4例因患肝癌死亡。其他患者一般情况良好 ,能进普食或半流食 ,能参加轻度体力劳动 ,肝功能基本正常 ,脾亢症状缓解 ,白细胞和血小板计数基本维持在正常范围。结论 尽管早、中期分流道再狭窄发生率较高(占 34 % ) ,但大部分病例可通过溶栓、球囊扩张或内支架置入获得再通 ,有相当数量的病例 ,能保持中长期的有效分流。在急性消化道大出血时 ,TIPSS仍是一种很有价值的实用技术。
Objective To study the 6 year outcome following transjugular intrahepatic portosystemic shunt (TIPSS) for variceal bleeding due to portal hypertension. Methods 65 patients, 51 males, 14 females, aged 35～72 years old with averaged 4.5 years, have been undergone TIPSS because of portal hypertension due to cirrhosis or Budd Chiari syndrome. The portal pressures were measured before and after TIPSS. Follow up study was done by color Doppler sonography or Barium esophageal radiogaphy for 3 months to 6 years (averaged 18 months). Repeated interventional treatments were done in cases of restenosis of the shunts. Results There were 0,2,10,5,0 cases of recurrent bleeding after 3 months, 6 months, 1 year, 2 year and 3—6 year following TIPSS respectively. Stenosis occurred in shunt paths due to thrombosis or smooth muscle cell proliferation or neointimal hyperplasia were relieved after thrombolytic therapy and repeated balloon angioplasty or stent plant among most of them. 2 were failed due to serious stenosis. 7 cases died, 2 of massive bleeding, 1 of the other cause and 4 of hepatic cancer. The other patients are getting well. Conclusions Although there were very high rates of restenosis (34%), but most of them could be treated again with interventional therapy, and in kept patency effectively. TIPSS is a still practical valuable management for massive gastric bleeding.
出处
《介入放射学杂志》
CSCD
2002年第2期85-88,共4页
Journal of Interventional Radiology
