摘要
目的 :观察七叶皂苷治疗周围性面神经炎的疗效。方法 :七叶皂苷组 30例 ,用七叶皂苷 10～2 0mg加入氯化钠注射液 2 5 0mL中静脉滴注。地塞米松组 2 8例用地塞米松 10～ 2 0mg加入氯化钠注射液 2 5 0mL中静脉滴注。 2组同时应用B族维生素及胞磷胆碱等药物 ,同在用药 14d后判定疗效。结果 :七叶皂苷组痊愈 2 3例 ,好转 5例 ,无效 2例 ,有效率 93%。地塞米松组痊愈 19例 ,好转 4例 ,无效 5例 ,有效率 82 % (P >0 .0 5 )。地塞米松组副作用大于七叶皂苷组。结论 :七叶皂苷副作用小 ,毒性低 ,适应范围广 ,是治疗周围性面神经炎的较好药物。
AIM: To observe the efficacy of aescine in treating facial neuritis. METHODS: Aescine group of thirty patients (M 17,F 13; age 52 a± s 12 a) was treated with aescin 10 20 mg in sodium chloride injection 250 mL, iv, drip, qd. Other patients (M 18,F 10; age 51 a±11 a) as dexamethasone group were treated with dexamethasone 10 15 mg in sodium chloride injection 250 mL, iv,drip, qd. The therapeutic couse was 14 d. RESULTS: The total effective rates were 93 % for aescine group and 82 % for dexamethasone group ( P >0.05). The adverse reactions in dexamethasone group were higher than that in aescine group. CONCLUSION: Aescine is a better drug in the treatment of patients with facial neuritis.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2002年第4期224-225,共2页
Chinese Journal of New Drugs and Clinical Remedies
关键词
七叶皂苷
治疗
周围性面神经炎
疗效
aescine
facial paralysis
peripheral nerve system diseases
