摘要
目的 : 探讨梅毒螺旋体特异性抗体胶体金法 (TPAb)对梅毒诊断的实用性和优越性。方法 : 用TPAb法对梅毒患者、非梅毒患者血清进行检测 ,同时与快速血浆反应素试验 (RPR)和梅毒螺旋体血凝试验 (TPHA)相比较。结果 : TPAb法检测一期梅毒 2 1例敏感性为 71.4 3% ,高于RPR法 (5 7.14 % )及TPHA法 (6 6 .6 7% ) ;二期梅毒 6 4例 ,TPAb法及TPHA法检测敏感性均为 10 0 % ,高于RPR法 (92 .19% )。同时对 12 5例非梅毒患者血清进行了检测 ,结果全部阴性 ,特异性为 10 0 %。结论 : TPAb法具有较高敏感性和特异性而且简单、方便、快速 。
Objectives: To determine the applicability and superiority of TPAb assay in the diagnosis of syphilis.Methods:TPAb was used to detect the specific antibody of syphilis in serum from syphilis and non syphilis patients and compared with RPR and TPHA. Results: In 21 primary syphilis patients, the sensitivity of TPAb, TPHA and RPR was 71.43%, 66.67% and 57.14%, respectively. In 64 secondary syphilis patients, the sensitivity of TPAb, TPHA and RPR was 100%, 100% and 92.19%, respectively. In 125 non syphilis patients, the specificity of TPAb was 100%. Conclusion : TPAb is a sensitive, specific, simple and rapid method, which can be used in syphilis diagnosis.
出处
《中国麻风皮肤病杂志》
北大核心
2002年第1期14-15,共2页
China Journal of Leprosy and Skin Diseases
关键词
胶体金法
重组TP抗原
梅毒
诊断
colloidal gold
recombinated TP antigen
syphilis diagnosis
