摘要
通过6只大的腹腔化疗,测得腹腔液、股静脉和门静脉的血药浓度,以及数理模型的推导,给出顺铂在体内药物扩散、药物吸收及吸收速率函数.其结呆不仅给临床顺铂腹腔化疗提供理论依据而且提出研究体内药物释放,药物吸收量及药物吸收速率的方法.
Through the peritoneal chemotherapy performed on 6 dog's measured celiac fluid, femoral vein and portal vein b1ood drug concentration. The mathematical logic infered the mathematical function of drug diffusion, absorption and absorptive rate. The results provided clinical basis for cisplatin isotone peritoneal chemotherapy as well as established a method for the research of drug release, absorbed dose and absortive rate.
出处
《生物数学学报》
CSCD
2002年第1期55-59,共5页
Journal of Biomathematics