摘要
天然酶经表面活性剂包衣后在有机溶剂中的活性和对映选择性有显著提高 ,稳定性也大为改善。目前研究涉及的大多为酯化或酯交换反应 ,使用最多的为脂肪酶 ,底物的分子结构对包衣酶的对映选择性有显著影响。指出可以借助膜反应器来实现包衣酶的截留和反复利用及产物的分离 ,通过改良表面活性剂或改进包衣酶的制备过程可望进一步提高包衣酶的收率和活性 ,包衣酶催化反应的机理及动力学也有待深入研究。
The activity and the enantiotropic selectivity of native enzymes coated with surfactants are remarkably increased and the stability is also greatly improved. Present researches mainly focus on esterification and trans-esterification reactions mostly catalyzed by lipases. The substrate molecular structure has a great effect on the enantiotropic selectivity of coated enzymes. It was pointed out that membrane reactors might be used to retain surfactant-coated enzymes for reuse and also to separate products. The yield and the activity of surfactant-coated enzymes could be further increased by improving the structure of surfactants or by optimizing the preparation of surfactant-coated enzymes. Mechanisms and kinetics of the catalytic reaction of surfactant-coated enzymes also needed further investigation.
出处
《现代化工》
EI
CAS
CSCD
北大核心
2002年第2期15-17,共3页
Modern Chemical Industry
基金
国家自然科学基金 (2 98760 31 )
教育部归国留学人员启动基金资助项目
关键词
包衣酶
酶
表面活性剂
对映异构体
拆分
有机溶剂
Esterification
Mechanisms
Optical resolving power
Organic solvents
Reaction kinetics
Surface active agents
