摘要
目的了解三种不同药物用于局麻病人自控镇静 (PCS)效果及药物不良反应。方法将 4 5例局麻下行上颌窦根治手术病人随机分为 A、B、C三组各 15例 ,分别于手术开始前给予异丙酚、咪唑安定、氟哌利多加芬太尼行PCS。结果镇静效果均满意 ,其中 A组起效最快 (平均 86 .4 s) ,B组次之 (平均 14 9.8s) ,C组起效最慢 (平均 16 9.6s) ;A组与 B、C组比较 ,均 P<0 .0 1,差异有极显著性意义。术中、术毕、术后 30 m in记忆缺失状况 ,术中 B组较 A、C组差 (均 P<0 .0 1) ;术毕及术后 30 min C组较 A、B组差 (P<0 .0 1,P<0 .0 5 )。结论 A组 (异丙酚 )镇静效果好 ,恢复快 ,最适用于 PCS。
Objective To assess the sedation and side effects of three different drugs applied in patient controlled sedation (PCS) in the patients under local anesthesia. Methods Forty five patients undergoing radical maxillary antrectomy under local anesthesia were divided into groups A, B and C. Before the operation, propofol (group A), Midazolum (group B) and Droperiodol Fentanyle (group C) was given respectively for PCS.Results All patients in the 3 groups had satisfactory effects. The average onset time of the drug effect in the group A was 86.4 s, which was the quickest, followed by group B (149 8 s) and group C (169 6 s which was the slowest).Conclusion Propfol is more surtable for PCS due to its ideal sedation effect, rapid onset and fast recovery.
出处
《护理学杂志（综合版）》
2002年第4期255-257,共3页
Journal of Nursing Science
