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妊娠高血压综合征大鼠胎盘组织血管紧张素Ⅱ的研究 被引量:2

Determination of angiotensin Ⅱ in placenta tissue of preeclampsia rat
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摘要 目的 探讨胎盘组织中血管紧张素 与妊娠高血压综合征 (妊高征 )发病的关系。方法 用放射免疫法测定妊高征大鼠 (15只 )及正常妊娠大鼠 (5只 )胎盘组织中血管紧张素 水平。结果 妊高征大鼠胎盘组织中血管紧张素 水平〔(2 5 1± 38) pg/ mg〕较正常妊娠大鼠〔(132± 30 ) pg/ m g〕明显增高 (P<0 .0 0 1)。结论 胎盘组织血管紧张素 Objective To explore the relation of preeclampsia with the angiotensin Ⅱ level in placenta tissue.Method Placenta tissue angiotensin Ⅱ levels were detected by radioimmunoassay in 15 preeclampsia rats and 5 normal pregnant rats.Results The angiotensin Ⅱ levels of placenta tissue in preeclampsia rats 〔(251±38)pg/mg〕 were significantly higher than those in normal pregnant rats 〔(132±30)pg/mg P<0.001〕.Conclusion Angiotensin Ⅱ in placenta tissue may play a key role in the development of preeclampsia.
出处 《山西医药杂志》 CAS 2002年第2期109-110,共2页 Shanxi Medical Journal
基金 太原市科技启明星项目资助 (982 0 72 )
关键词 胎盘 血管紧张素Ⅱ 放射免疫法 妊娠高血压综合征 大鼠 Gestosis,edema,proteinuria,hypertension Preeclampsia Placenta Angiotensin Ⅱ
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参考文献6

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二级参考文献7

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