摘要
目的 :探讨咪唑安定清醒镇静用于胃镜检查所需的剂量与年龄、性别的相关性 ,并观察其镇静效果及对呼吸循环的影响。方法 :2 10例胃镜检查患者 ,先给予咪唑安定 0 .0 2mg/kg,以后追加 0 .0 1mg/kg至OAA/S评分达 3分止。记录所需咪唑定安剂量 ,并记录检查过程中MAP ,HR ,SpO2 和BIS的变化及检查后患者的遗忘度、满意度。结果 :咪唑安定用于胃镜检查是安全有效的 ,其所需剂量与年龄呈明显负相关 (男性γ =- 0 .784,女性γ =- 0 .76 2 ,P <0 .0 1) ,而与性别无相关性。结论 :咪唑安定清醒镇静用于胃镜检查所需剂量与年龄成负相关。
Objective:To study of relating dose of midazolam to age and sex in gastroscopy on conscious sedation.Methods:Two hundred and ten patients undergone gastroscopy were intravenously given midazolam (0.02mg/kg),after tow minutes,further increments of midazolam (0.01mg/kg) were given until the appropriate level of consciousness (OAA/S=3) was reached.The age,sex and total dose of midazolam given to each patient was recorded.The BIS,MAP,HR and SpO 2 were measared.Results:The midazolam could produced safe and effective sedation for gastroscopy.There was a strongly relationship in both males and females between the dose of midazolam used and the subject's age (γ=-0.784, P <0.01 for males,and γ=-0.762, P <0.01 for females).The mean dose of midazolam required in the male patients was slightly greater the female,but this was not significant.Conclusions:There is a strong relationship between the dose of midazolam used and the subject's age.
出处
《中国内镜杂志》
CSCD
2002年第2期50-51,共2页
China Journal of Endoscopy
