摘要
目的 :为了探讨苯那普利和硝苯地平缓释片对于清晨血压 ,心率及心率收缩压乘积的效果。方法 :选取 6 0例轻、中度高血压患者 ,分别给予苯那普利或硝苯地平缓释片治疗。利用动态血压监测观察治疗前和 2 0d后清晨血压 ,心率及心率收缩压乘积的变化。结果 :两种药物对清晨血压下降无统计学差异 ,而在清晨心率和心率收缩压乘积有统计学差异。结论 :苯那普利组清晨心率轻微下降 ,硝苯地平缓释片组则稍上升 ,苯那普利组清晨心率收缩压乘积下降更明显。
Objective: To assess the effects of Benazepril and Nifedipine retard on the morning blood pressure(BP),heart rate (HR)and HR-systolic BP product. Methods: 60 patients with mild or moderate hypertension were selected and Benazepril or Nifedipine retard were given respectively. The morning BP, HR and HR-systolic BP product were observed through the 24 hour ambulatory blood pressure monitoring at the baseline and 20 days after treatment. Results: The decrease on morning blood pressure showed no difference, however, the effects of the two medicines on morning HR and HR-systolic BP product were significantly different. Morning HR was slightly decreased in Benazepril group, while Nifedipine retard group raised HR. Conclusions: In Benazepril group, the morning HR-systolic BP product was lowered to a greater extent than in Nifedipine retard group.
出处
《内科急危重症杂志》
2002年第1期16-17,共2页
Journal of Critical Care In Internal Medicine
