摘要
目的报道1例听神经鞘瘤合并垂体腺瘤的罕见病例,提高对颅内多发性原发肿瘤的认识。方法总结1例听神经鞘瘤合并垂体腺瘤患者的临床资料并结合复习相关文献报道进行讨论。结果包括本病例及文献报道共20例听神经鞘瘤合并垂体腺瘤患者,其中男性11例、女性9例,临床表现多样,多为听神经鞘瘤和(或)垂体腺瘤症状的组合,MRI检查为明确病灶的主要手段。治疗通常采用药物、立体定向放射外科或手术切除治疗,部分无症状患者可随诊观察。结论听神经鞘瘤和垂体腺瘤并存临床罕见,病因尚不明确,可能与环境、遗传倾向性及遗传基因的改变等多种因素相关。随着病例积累和开展深入研究有助于提高临床医生的认识。
Aim To report one rare case of vestibular schwannoma( VS) coexisting with pituitary adenoma( PA). Methods A case of vestibular schwannoma coexisting with pituitary adenoma was summarized and the related literature were reviewed. Results There were 20 patients with concomitant VS and PA( including 11 males and 9 females) reported. The clinical manifestations of the diseases are various,mostly the combination of VS and/or PA symptoms. Magnetic resonance imaging( MRI) is the main means of defining the focus. The treatment including medical,stereotactic radiosurgery( SRS) or surgery,some asymptomatic patients can be observed. Conclusion The coexistence of VS and PA is a rarecondition,which currently etiology still unclear. Further study of this population may help elucidate the cause of multiple primary intracranial tumors.
作者
金古钰
刘辉
李靖宇
JIN Gu-yu;LIU Hui;LI Jing-Yu(Graduate School of Dalian Medical University,Dalian 116044,China;967 Hospital of PLA,Dalian 116021,China)
出处
《中国临床神经科学》
2019年第1期59-64,共6页
Chinese Journal of Clinical Neurosciences
关键词
听神经鞘瘤
垂体腺瘤
颅内多发性原发肿瘤
神经影像学
vestibular schwannoma
pituitary adenoma
multiple primary intracranial tumors
neuroimaging
