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盐酸纳布啡注射液用于剖宫产术后镇痛的临床效果及其对产后抑郁的预防作用 被引量:9

Clinical effect of nalbuphine hydrochloride injection for analgesia after cesarean section and its preventive effect on postpartum depression
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摘要 目的分析盐酸纳布啡注射液在剖宫产术后镇痛中的应用效果及其对产后抑郁产生的预防作用。方法收集2016年9月-2017年10月于院内行剖宫产分娩的118例足月产妇患者的临床资料进行回顾性分析,根据患者的剖宫产术后镇痛药物不同将其分为A组(61例)和B组(57例),A组和B组产妇术后分别使用盐酸纳布啡注射液和舒芬太尼进行镇痛,对比两组产妇的镇痛效果及产后抑郁发生率。结果 A组的产后疼痛评分均明显低于B组(P<0.05),但两组产妇的镇静评分相比差异无统计学意义(P>0.05);A组的产后抑郁发生率和不良反应发生率分别为0和3.28%,均明显低于B组(P<0.05)。结论盐酸纳布啡注射液可以有效应用于剖宫产术后的镇痛治疗中,有利于降低产妇的产后抑郁发生率,宜广泛应用和推广。 Objective To analyze the effect of nalbuphine hydrochloride injection in postoperative analgesia after cesarean section and its preventive effect on postpartum depression. Methods The clinical data of 118 cases of term parturient who were delivered by cesarean section from September 2016 to October 2017 were retrospectively analyzed. According to the analgesic drugs after cesarean section, the patients were divided into two groups: the group A(61 cases), the group B(57 cases)and the group B(57 cases)were treated with naporphine hydrochloride and sufentanil respectively. The analgesic effect and the incidence of postpartum depression were compared between the two groups. Results Postpartum pain scores in the group A were significantly lower than that of the group B(P <0.05), but there was no significant difference in the sedation score between the two groups(P > 0.05). The incidence of postpartum depression and adverse reaction in the group A 0 and 3.28% respectively, which were significantly lower than that of the group B(P <0.05). Conclusion Naporphine hydrochloride injection can be used effectively in the analgesic treatment of cesarean section, which is helpful to reduce the incidence of postpartum depression, and should be widely used and popularized.
作者 李勇 郭大力 LI Yong;GUO Da li(Department of Anesthesiology,Xinjiang Jiayin Hospital,Urumqi,Xinjiang 830054,China)
出处 《新疆医学》 2018年第10期1124-1126,共3页 Xinjiang Medical Journal
关键词 盐酸纳布啡注射液 剖宫产 术后镇痛 产后抑郁 Nalbuphine Hydrochloride Injection Cesarean Section Postoperative Analgesia Postpartum Depression
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