摘要
目的观察自膨胀式金属支架(SEMS)治疗癌性结直肠梗阻的临床疗效,并分析相关影响因素。方法回顾性分析2012年3月-2017年12月北京海淀医院收治的47例行SEMS治疗的癌性结直肠梗阻患者的相关临床资料,患者术后通过门诊和电话随访,应用SPSS17.0软件统计治疗有效率、患者生存率及并发症情况,x^2检验分析相关影响因素。结果SEMS的临床有效率为100%(47/47)。患者的30 d生存率为87.2%(41/47),6个月生存率为68.1%(32/47);患者中分别发生2例穿孔、3例位移、5例再梗阻。分析结果显示,肿瘤临床分期、支架长度与SEMS术后并发症和生存率有关(P<0.05)。临床晚期的患者并发症发生率及病死率率风险均高于早期患者;SEMS支架较长(10-12cm),则并发症及病死率风险较高。而性别、年龄、ECOG评分及治疗方案与并发症和生存率未见明显相关性。结论肿瘤临床分期和支架长度可能是SEMS术后并发症和患者生存率的危险因素。
Objective To .analyze the clinical efficacy and relative influence factors of self-expanding metallic stents (SEMS)in treating colorectal cancer obstruction.Methods Information of 47 patients received SEMS to treat colorectal cancer obstruction from Mar.2012 to Dec.2017 in Beijing Haidian Hospital were collected,who were then followed up in outpatient or by telephone.Effective rate,survival rate and complications were recorded and calculated by the software of SPSS 17.0.Chi-square test was used to analyze relative influence factors.Results Results shown that the clinical efficacy was 100%(47/47).Patients 30-day survival rate and 6-month survival rate were 87.2% (41/47)and 68.1%(32/47),respectively.After surgery,2 patients presented with perforation,3 patients presented with migration and 5 patients presented with reobstruction.Clinical stage of tumor and stent length were related with complications and survival.Therein,complications presented more in patients with advanced cancer.And the longer stent length,the higher mortality.Conclusions Clinical stage of tumor and stent length maybe risk factors of complications and survival of patients after SEMS surgery of colorectal cancer obstruction.
作者
刘铭
郭银燕
刘凯东
张乐
赵晓志
庆琳琳
尚杰
白月奎
Liu Ming;Guo Yinyan;Lin Kaidong;Zhang Le;Zhao Xiaozhi;Qing Linlin;Shang Jie;Bai Yuekui(Department of General Surgery,Beijing Haidian Hospital,Beijing 100080,China)
出处
《国际外科学杂志》
2018年第12期820-824,共5页
International Journal of Surgery
关键词
支架
肠梗阻
结直肠肿瘤
疗效
生存率
影响因素
Stents
Intestinal obstruction
Colorectal neoplasms
Efficacy
Survival rate
Influence factors
