摘要
目的探讨电针穴位刺激对结直肠癌患者术中静脉麻醉药物剂量的影响。方法选择行开腹结直肠癌根治术患者60例,年龄18～59岁,ASAⅠ～Ⅲ级。将患者随机分为全凭静脉组(C组)、电针刺激EA1组、电针刺激EA2 3组,每组20例。3组均行全凭静脉麻醉; EA1组术前1 d,EA2组术前1 d、术前30 min行电针刺激,穴取中脘及右侧天枢、内关、足三里、上巨虚、下巨虚,持续30 min。记录患者入室(Ta)、术中腹腔冲洗后(Tb)、术毕(Tc)平均动脉压(MAP)、心率(HR)、指脉氧饱和度(Sp O_2),手术时间、麻醉时间及术后睁眼时间,术中丙泊酚、瑞芬太尼、顺苯磺酸阿曲库铵用量。结果各组不同时点MAP、HR、SpO_2组间比较,差异无统计学意义(P> 0. 05);手术时间、麻醉时间、术后睁眼时间比较,差异无统计学意义(P> 0. 05);丙泊酚、顺苯磺酸阿曲库铵用量比较,差异无统计学意义(P> 0. 05),与C组、EA1组比较,EA2组瑞芬太尼的用量减少(P <0. 05)。结论电针穴位刺激具有时效性,术前30 min电针刺激可减少术中瑞芬太尼的用量,但对其他药物用量无明显影响。
Objective To investigate whether there exists an influence on dose of anesthetics in intravenous anesthesia via electro-acupuncture( EA) in the patients with colorectal cancer surgery. Methods Sixty patients with colorectal cancer about to took an elective surgery,aged from 18 to 59,graded ASAⅠ ~ Ⅲ,were randomly divided into three groups,with 20 in each group: Group C( total intravenous anesthesia),Group EA1( total intravenous anesthesia combined with EA stimulation 24 hours before surgery),Group EA2( total intravenous anesthesia combined with EA stimulation 24 hours and 30 minuite before surgery). Groups EA1 and EA2 received EA pretreatment at Zhongwan( CV 12) and right Tianshu( ST 25),Zusanli( ST 36),Neiguan( PC 6),Shangjuxu( ST 37),xiajuxu( ST39). All EA treatments lasted 30 min. We recorded mean arterial pressure( MAP),heart rate( HR) and finger pulse oxygen saturation( SpO2) at three time points-after patients entering the room( Ta),peritoneal lavage( Tb) and the end of operation( Tc). Surgical operation time,anesthesia time and eye opening time upon calling were analyzed. We also recorded propofol,remifentanil and cisatracurium dosage. Results There was no significant difference in preoperative( Ta),intraoperative( Tb),postoperative( Tc) mean arterial pressure( MAP),heart rate( HR),pulse oxygen saturation( SpO2) between groups( P > 0. 05). Groups of patients with operation time,anesthesia time and postoperative awake time had no significant difference( P > 0. 05),each group of propofol and cisatracurium besylate were not statistically significant( P > 0. 05) compared with C group,EA1 group,and EA2 group reduced the amount of remifentanil( P <0. 05). Conclusion Electro acupuncture stimulation has time effect,and preoperative 30 min electroacupuncture can reduce the dosage of remifentanil,but have no significant influence on the dosage of propofol and cisatracurium besylate.
作者
王天渊
孟尽海
麦思聪
WANG Tianyuan;MENG Jinhai;MAI Sicong(Department of AnesthesioIogy,Nin'gxia People's Hospital,Yinchuan 750021,China;Department of Anesthesiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)
出处
《宁夏医学杂志》
CAS
2018年第12期1110-1112,共3页
Ningxia Medical Journal
关键词
结直肠癌开腹手术
电针
麻醉药物
Colorectal cancer laparotomy
Electroacupuncture
Intravenous anesthetics
