摘要
目的通过数据挖掘探索男性急性痛风性关节炎的中医证候特点。方法采集316例男性急性痛风性关节炎病例症状信息,将每一症状作为一个统计变量,有赋值为1、无赋值为0,计算各症状的频次和频率,对主要症状进行因子分析并提取公因子,以公因子作为变量进行聚类分析。结果频率超过30%的症状为舌红(62. 0%)、舌胖大(56. 3%)、疲劳(45. 6%)、关节灼痛(42. 7%)、口苦(38. 3%)、脉数(36. 1%)、关节冷痛(32. 6%)、胃胀(32. 3%)、畏寒(30. 1%),提取公因子共10项,总贡献率累计69. 667%。聚类分析获得男性急性痛风性关节炎辨证分型5种,分别为脾肾阳虚型、痰热内蕴型、热毒炽盛型、肝肾亏虚型、阳虚湿阻型。结论男性急性痛风性关节炎的主要中医证型可分为5种,但临证应注意结合患者的病程、年龄、体质等因素具体论治。
Objective To explore the characteristics of traditional Chinese medicine(TCM)syndrome of male acute gout arthritis by data mining.Methods The symptom information of 316 male patients with acute gout arthritis was collected.Each symptom was used as a statistical variable,assigning value 1 or 0 for "with"or "without"a symptom.The frequency and frequency rate of each symptom were calculated.Factor analysis was performed on the main symptoms and common factors were extracted.Clustering analysis was performed using the common factor as a variable.Results The symptoms with a frequency rate more than 30% were red tongue(62.0%),fat tongue(56.3%),fatigue(45.6%),joint burning(42.7%),bitter mouth(38.3%),rapid pulse(36.1%),joint cold pain(32.6%),stomach distension(32.3%),and aversion to cold(30.1%).A total of 10 common factors were extracted.The total contribution rate was 69.667%.Clustering analysis obtained 5 types of male acute gout arthritis syndrome differentiation including spleen-kidney yang deficiency type,internal accumulation of phlegm-heat type,heat-toxic flaming type,liver-kidney deficiency type,and yang deficiency and damp obstruction type.Conclusion The main TCM syndrome differentiation pattern of male acute gout arthritis can be divided into 5 types,but the clinical syndrome should be combined with the specific treatment of the patient’s disease course,age,physical constitution and other factors.
作者
李壮
侯堃
LI Zhuang;HOU Kun(Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078;Beijing Hospital of Traditional Chinese Medicine, Capital Medical University)
出处
《中医杂志》
CSCD
北大核心
2019年第1期47-50,共4页
Journal of Traditional Chinese Medicine
基金
北京中医药大学2017年度基本科研业费项目(2017-JYBJS-190)
关键词
急性痛风性关节炎
证候
证候分类
因子分析
聚类分析
acute gout arthritis
traditional Chinese medicine syndrome
classification of syndromes
factor analysis
clustering analysis
