摘要
Dear Editor, Hepatitis B Virus(HBV)infection remains a major health problem worldwide despite the availability of a highly ef- fective preventive vaccine.HBV genome codes several distinct proteins,among which the non-particulate e-antigen(HBeAg)is one of the important markers in HBV infection. Sera containing HBeAg are highly infectious but those with anti-HBeAg have little infectivity.
基金
supported by the National Natural Science Foundation of China (31470036)