摘要
目的探讨动脉介入与经皮穿刺消融联合治疗肝癌患者的效果。方法选取大同市第五人民医院2015年8月至2017年3月收治的78例预估生存期6个月以上的肝癌患者进行研究。采用随机数字表法将患者均分为两组,每组39例。观察组采用股动脉穿刺介入治疗肝脏肿瘤并联合经皮穿刺消融方法。对照组采用股动脉穿刺介入治疗肝脏肿瘤,统计两组患者治疗效果,并检测肿瘤标记物甲胎蛋白水平,调查统计78例患者生活质量与骨髓抑制率。结果观察组患者生活质量、治疗总有效率优于对照组,差异有统计学意义(P<0.05)。观察组骨髓抑制率低于对照组,差异有统计学意义(P<0.05)。观察组肿瘤标记物甲胎蛋白水平低于对照组,差异有统计学意义(P<0.05)。结论动脉介入与经皮穿刺消融联合治疗肝癌患者有利于降低不良反应发生率,改善预后与提高生活质量,并且其临床疗效优于单一治疗,可明显降低肿瘤标记物甲胎蛋白表达水平。值得临床应用和推广。
ObjectiveTo investigate the efficacy of arterial intervention and percutaneous puncture ablation on patients with liver cancer.MethodsSeventy-eight patients with hepatocellular carcinoma who were scheduled to survive for more than 6 months from August 2015 to March 2017 in the Fifth People's Hospital of Datong were randomly divided into two groups using random number expression, with 39 cases in each group. Thirty-nine patients in the observation group were treated with femoral artery puncture to treat liver tumors and combined with percutaneous puncture ablation. In the control group, 39 patients were treated with femoral artery puncture to treat liver tumors. The therapeutic effects in the two groups were statistically analyzed. The expression level of alpha-fetal protein was measured. The quality of life and bone marrow suppression rate were investigated in 78 patients.ResultsThe quality of life and total effective rate of treatment in the observation group were significantly better than those in the control group(P<0.05). The bone marrow suppression rate in the observation group was significantly lower than that in the control group(P<0.05). The level of alpha-fetoprotein in the observation group were lower than that in the control group(P<0.05).ConclusionsArterial intervention and percutaneous puncture ablation combined treatment of patients with liver cancer is beneficial to reduce the incidence of adverse reactions, improve the prognosis and the quality of life. And its clinical efficacy is significantly better than single treatment, which can significantly reduce the level of alpha-fetal protein. It is worthy of clinical application and promotion.
作者
张新
Zhang Xin(Department of Intervention,the Fifth People's Hospital of Datong,Datong 037006,China)
出处
《中国实用医刊》
2018年第22期34-36,共3页
Chinese Journal of Practical Medicine
关键词
动脉介入治疗
经皮穿刺消融
肝癌
Artery interventional therapy
Percutaneous puncture ablation
Liver cancer
